Primary inflammatory malignant fibrous histiocytoma of the breast: A case report of an unusual variant and review of the literature

Mesenchymal breast lesions

“…43 Cases in the breast may be associated with a history of radiation or other breast malignancy, especially malignant phyllodes tumour. 44,45 Breast MFH affects middle-aged to elderly females, and less often occurs in elderly males. 44,46,47 On clinical examination, a breast MFH presents as a painless palpable mass that the patient reports appeared over a short time.…”

“…44,45 Breast MFH affects middle-aged to elderly females, and less often occurs in elderly males. 44,46,47 On clinical examination, a breast MFH presents as a painless palpable mass that the patient reports appeared over a short time. 44,47 One series of nine patients described the presentation as a painless breast mass in all patients.…”

“…44,46,47 On clinical examination, a breast MFH presents as a painless palpable mass that the patient reports appeared over a short time. 44,47 One series of nine patients described the presentation as a painless breast mass in all patients. 48 Alternatively, cases have also been reported of slowly growing or painful masses.…”

“…45,47 MFHs are sarcomas made of fibroblast-like and histiocyte-like cells mixed with pleomorphic giant and inflammatory cells. 44,48,50 They contain mesenchymal markers. 48 In the past, they were divided into three subtypes: storiformepleomorphic MFH, giant cell MFH, and inflammatory MFH.…”

“…At mammography, MFH may be evident as a mass that is denser than the surrounding breast tissue. 44,51,52 The margins vary: cases have been reported with both well-circumscribed and indistinct margins. 45,51,52 MFH typically lack calcifications.…”