Primary Intracardiac Yolk Sac Tumor

Parvathy, Usha; Balakrishnan, K.R.; Ranjit, M. S.; Kuruvilla, Sarah; Rao, K R Prasada

doi:10.1007/s002469900368

Cited by 10 publications

(4 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Myocardium is an extremely rare site of origin for an extra gonadal GCT and only 3 cases have been reported. All previously documented tumours are also yolk sac or predominantly yolk sac in origin [3,4,5]. Our patient differs from the previously reported cases in that the tumour was arising from the endocardium and focally infiltrating the myocardium rather than originating in the myocardium itself.…”

Section: Discussioncontrasting

confidence: 55%

A case of intra cardiac yolk sac tumour

Amalaseelan¹,

Pieris

Munasinghe

2010

Ceylon Med. J.

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 55%

A case of intra cardiac yolk sac tumour

Amalaseelan¹,

Pieris

Munasinghe

2010

Ceylon Med. J.

View full text Add to dashboard Cite

“…Surgical biopsy or resection may be performed depending on the site and extent of tumors. 38 Surgical resection may offer symptomatic relief and life prolongation. 38…”

Section: Malignant Fetal Cardiac Tumormentioning

confidence: 99%

Fetal Primary Cardiac Tumors During Perinatal Period

Yuan

2017

Pediatrics & Neonatology

View full text Add to dashboard Cite

Fetal primary cardiac tumors are rare, but they may cause complications, which are sometimes life threatening, including arrhythmias, hydrops fetalis, ventricular outflow/inflow obstruction, cardiac failure, and even sudden death. Among fetal primary cardiac tumors, rhabdomyomas are most common, followed by teratomas, fibromas, hemangiomas, and myxomas. Everolimus, a mammalian target of rapamycin inhibitor, has been reported to be an effective drug to cause tumor remission in three neonates with multiple cardiac rhabdomyomas. Neonatal cardiac surgery for the resection of primary cardiac tumors found by fetal echocardiography has been reported sporadically. However, open fetal surgery for pericardial teratoma resection, which was performed successfully via a fetal median sternotomy in one case report, could be a promising intervention to rescue these patients with large pericardial effusions. These recent achievements undoubtedly encourage further development in early management of fetal cardiac tumors. Owing to the rarity of fetal primary cardiac tumors, relevant information in terms of prenatal diagnosis, treatment, and prognosis remains to be clarified.

show abstract

“…There are few reported cases of yolk sac tumor with intracardiac involvement, specifically of the right ventricle. A review of the literature revealed two reports of primary intracardiac yolk sac tumors: a two-year-old male and a three-year-old female [ 9 , 10 ]. In 2013, Nunes et al published a comprehensive review of germ cell tumors with intracardiac involvement [ 11 ], totaling 18 cases including their own cases.…”

Section: Discussionmentioning

confidence: 99%

Right Ventricular Heart Failure from a Cardiac Yolk Sac Tumor

et al. 2018

View full text Add to dashboard Cite

Patient: Male, 46Final Diagnosis: Yolk Sac tumorSymptoms: Shortness of breathMedication: —Clinical Procedure: Cardiac MRI • tumor resectionSpecialty: CardiologyObjective:Rare diseaseBackground:Cardiac involvement by a malignant tumor is rare. However, this is a case of right heart failure due to cardiac metastasis from a yolk sac tumor. Although a few case reports of cardiac metastasis from yolk sac tumors have been published, to our knowledge this is the first instance of multiple metastases to the right ventricular of yolk sac tumor in an adult male.Case Report:The patient is a 46-year-old male with a history of testicular cancer that presented with dyspnea on exertion. He was found to have two large right sided intracardiac masses on echocardiography. Cardiac magnetic resonance imaging (MRI) was obtained to further investigate these masses. Right ventricular function was decreased and concern for right ventricular outflow tract (RVOT) obstruction was present. The patient was taken to the operating room (OR) for resection of the cardiac masses. Pathology revealed the masses to be yolk sac tumors. Despite urgent resection of the tumors, the patient deteriorated clinically, ultimately succumbing to heart failure.Conclusions:This unique presentation of a yolk sac tumor emphasizes the need to keep a broad differential and complete a thorough workup for any cardiac mass. Early diagnosis and treatment of intra-cardiac masses is imperative due to their high rates of mortality. Albeit an uncommon etiology for heart failure, germ cell tumors can potentially metastasize to the heart and present with such a clinical picture.

show abstract

Primary Intracardiac Yolk Sac Tumor

Cited by 10 publications

References 7 publications

A case of intra cardiac yolk sac tumour

A case of intra cardiac yolk sac tumour

Fetal Primary Cardiac Tumors During Perinatal Period

Right Ventricular Heart Failure from a Cardiac Yolk Sac Tumor

Contact Info

Product

Resources

About