Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non-tuberculous mycobacteria: A case report and review of the literature

Inagaki, Noriko; Kibata, Kayoko; Tamaki, Takeshi; Shimizu, Toshiki; Nomura, Shosaku

doi:10.3892/ol.2013.1461

Cited by 19 publications

(24 citation statements)

References 26 publications

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“…To our knowledge this is the eighth adult case of primary intrahepatic malignant mesothelioma reported in the literature. 2–8 There have been reports of mesotheliomas originating in the falciform ligament 9 or the liver surface, 10 which probably represent peritoneal mesotheliomas involving the liver.…”

Section: Discussionmentioning

confidence: 99%

Primary intrahepatic malignant epithelioid mesothelioma

Perysinakis

Nixon

Spyridakis

et al. 2014

International Journal of Surgery Case Reports

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Section: Discussionmentioning

confidence: 99%

Primary intrahepatic malignant epithelioid mesothelioma

Perysinakis

Nixon

Spyridakis

et al. 2014

International Journal of Surgery Case Reports

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“…Approximately 20-35% of all the MM are peritoneal, just next to pleural mesothelioma (60-65%) (1)(2)(3)(4). Peritoneal mesothelioma (PM) has characteristics of constant invasion of the adjacent visceral organs but infrequent metastasis to the liver (5)(6)(7). Besides secondary intrahepatic malignant mesothelioma (SIHMM), primary intrahepatic mesothelioma (PIHMM) was also reported with only less than 20 case reports from around the world so far, and is not yet included in the World Health Organization (WHO) classification of hepatic tumors (8).…”

Section: Introductionmentioning

confidence: 99%

Current status of malignant mesothelioma with liver involvement in China: A brief report and review of the literature

Zhou

Quan

Wang

2018

IRDR

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Primary and secondary intrahepatic malignant mesothelioma (PIHMM & SIHMM) caused by Peritoneal mesothelioma (PM) are extremely rare tumors and their clinicopathological characteristics remain unclear. The current study presented a case of a 63-year-old female with PIHMM and a literature review of Chinese case reports of SIHMM and PIHMM was performed. The patient received curative left hemihepatectomy because of a 5.5 × 5.0 × 4.0 cm mass occupying the II, III and the lateral portion of the IV segments and meanwhile tightly infiltrating the diaphragm (yellow arrow) was also observed. The pathological diagnosis was epithelial type PIHMM. Immunohistochemistry revealed that the tumor was positive for Calretinin, CK5/6, WT-1 and D2-40(N). The literature review included 11 studies and 6 case reports with a total of 293 PM patients accompanied with 31 SIHMM cases and then 3 case reports of PIHMM. SIHMM and PIHMM are extremely rare, easy to misdiagnose malignant tumors. Immunohistochemistry should be performed strictly in accordance with guidelines, which is crucial for pathological diagnosis. Comprehensive treatment of surgery combined with chemotherapy are mainstream methods for SIHMM and PIHMM. Also, exact survival data should be carefully explored so that objective evaluation of the efficacy of the treatment could be achieved.

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“…MPM has been reported to invade adjacent visceral structures, such as the liver, spleen, or pelvic organs [ 6 ]. To date, there are few reports of primary or secondary MPM in the liver, and each such report presents a single case [ 7 – 14 ]. In this study, our report identifies 5 patients with MPM invading the liver to clarify the characteristics of MPM invading the liver and to review cases with primary or invading MPM in liver.…”

Section: Introductionmentioning

confidence: 99%

Malignant Peritoneum Mesothelioma with Hepatic Involvement: A Single Institution Experience in 5 Patients and Review of the Literature

Guo

Liu

et al. 2016

Gastroenterology Research and Practice

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Malignant peritoneal mesothelioma with invasion of the liver is an invariably fatal disease. We aimed to clarify the characteristics of malignant peritoneal mesothelioma cases with liver involvement. The clinical presentation, computed tomography images, and immunohistochemical and histopathological features of 5 patients with malignant peritoneal mesothelioma and liver involvement were evaluated. The diagnosis was established by imaging and immune profiles of the tumours. A review of 8 cases with primary or invading malignant mesothelioma in liver is presented. All 5 mesothelioma cases were asbestos-related. CT images of malignant peritoneal mesothelioma with the liver involvement typically showed that the lesion grew inside the liver along the capsule and was possibly accompanied by capsule breakthrough and extrahepatic infiltration. The tumours exhibited a common epithelioid appearance in all 5 patients and most cases revealed positive Cal, CK, and MC with negative CEA and HeP. Different from our findings, the review of literature revealed that most malignant mesothelioma of liver was due to primary intrahepatic malignant mesothelioma. Finally, we concluded that the diagnosis of malignant peritoneal mesothelioma cases with liver invasion is reliably achieved by the history of asbestos exposure, the characteristic CT imaging, and immune profiles of the tumours.

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Primary intrahepatic malignant mesothelioma with multiple lymphadenopathies due to non-tuberculous mycobacteria: A case report and review of the literature

Cited by 19 publications

References 26 publications

Primary intrahepatic malignant epithelioid mesothelioma

Primary intrahepatic malignant epithelioid mesothelioma

Current status of malignant mesothelioma with liver involvement in China: A brief report and review of the literature

Malignant Peritoneum Mesothelioma with Hepatic Involvement: A Single Institution Experience in 5 Patients and Review of the Literature

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