Primary invasive carcinoma of vagina with third degree uterovaginal prolapse: a case report and review of literature

Abstract

Vaginal ulcer associated with long standing genital prolapse need careful evaluation (including punch biopsy) for underlying carcinoma. Treatment due to the rarity of this entity was controversial previously and current review of literature suggests surgical treatment with or without radiotherapy as the optimum treatment for early stage and radiotherapy for advanced stage vaginal carcinoma associated with genital prolapse. Early diagnosis with adequate treatment can minimize the morbidity and mortality associated with vaginal carcinoma.

Uterine Prolapse Complicated by Vaginal Cancer: A Case Report and Literature Review

“…In this case, we performed a vaginal hysterectomy to cure uterine prolapse, with partial vaginectomy to remove the vaginal carcinoma and anterior and posterior colporrhaphy, in addition to radiotherapy. Due to the rarity of this entity, the treatment was controversial according to the current and previous literature [4,15]. We believe that surgical treatment with or without radiotherapy is the optimum treatment for early-stage vaginal carcinoma associated with uterine prolapse.…”

Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors

“…This malignancy has also been found in patients with vaginal or utero-vaginal prolapse [23][24][25]. Anecdotal cases have been described in women who had undergone vaginoplasty for vaginal agenesis due to Rokitansky-Kuster-Hauser syndrome [26][27][28].…”

A rare case of verrucous carcinoma of the cervix in a patient with uterine prolapse

“…The carcinoma of the cervix and uterine prolapse are common in developing countries but the combination of these two is a rare occurrence 1,2 . Verrucous carcinoma is a rare variant of welldifferentiated squamous cell carcinoma which commonly occur in sites such as oral cavity, skin, and larynx 3 .…”