Primary jejunal angiosarcoma: an extremely rare tumor diagnosed by means of anterograde spiral enteroscopy

Jayaraman, Vijay; Wilkinson, Mark N.; Nagula, Satish; Siebel, Mariana de Jesus Oliva; Bucobo, Juan Carlos; Zee, Sui Y.; Buscaglia, J. M.

doi:10.1055/s-0030-1256397

Cited by 4 publications

(1 citation statement)

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“…Angiosarcomas may arise in any part of the body, but commonly occur in skin and superficial soft tissues, with its predilection sites in the head and neck[ 5 ]. Epithelioid angiosarcoma of the gastrointestinal tract is an extremely rare neoplasm, which is only described in individual case reports and case series[ 6 - 9 ], with a lack of demographic morbidity data. According to literatures, vascular tumors of the stomach constitute only 0.9%-3.3% of all gastric cancers[ 10 ], while colorectal angiosarcomas represent less than 0.001% of all colorectal neoplasms[ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Multifocal gastrointestinal epithelioid angiosarcomas diagnosed by endoscopic mucosal resection: A case report

Chen¹,

Dong²,

Chen³

et al. 2020

WJG

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BACKGROUND Epithelioid angiosarcoma is a vascular neoplasm that is among the most aggressive subtypes of sarcomas. Its involvement in the gastrointestinal tract is rare. We here report a case of multifocal gastrointestinal epithelioid angiosarcomas presenting with gastrointestinal bleeding. CASE SUMMARY A 77-year-old woman was admitted because of melena and dizziness for three months. Gastroscopy and colonoscopy were performed, revealing a centrally ulcerated hemorrhagic polypoid lesion in the gastric body and multiple polypoid lesions with blood clots and hemorrhagic tendency in the colon. Histopathological examination of routine endoscopic biopsy samples showed inflammation in the gastric mucosa and tubular adenomas in the colon. The polypoid lesions were removed by endoscopic mucosal resection. Immunohistochemistry suggested a final diagnosis of epithelioid angiosarcomas. The patient refused chemotherapy and died after three months. CONCLUSION Epithelioid angiosarcomas are characterized by highly vascular nature and tendency to cause gastrointestinal bleeding. Efforts to obtain histological findings using endoscopic mucosal resection are of great importance.

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