“…Sometimes, the tumor may display an infiltrative growth pattern and involve the cardiac valve or occupy two or more heart chambers (17 cases, 22.1%). Unlike cardiac myxoma, PCLMS rarely had a stalk, 35,40 and rarely originated from the interatrial septum. 18,20,41 Figure 1.Age and sex distribution is shown of patients with reported primary cardiac leiomyosarcoma.…”
Our findings suggest that primary cardiac leiomyosarcomas tend to be biologically more aggressive compared to their counterparts in other sites. However, complete resection and adjunctive chemotherapy or radiotherapy may help to increase the life expectancy.
“…Sometimes, the tumor may display an infiltrative growth pattern and involve the cardiac valve or occupy two or more heart chambers (17 cases, 22.1%). Unlike cardiac myxoma, PCLMS rarely had a stalk, 35,40 and rarely originated from the interatrial septum. 18,20,41 Figure 1.Age and sex distribution is shown of patients with reported primary cardiac leiomyosarcoma.…”
Our findings suggest that primary cardiac leiomyosarcomas tend to be biologically more aggressive compared to their counterparts in other sites. However, complete resection and adjunctive chemotherapy or radiotherapy may help to increase the life expectancy.
“…Table shows similar cases that survived for over 24 months with the available data regarding treatment modalities and outcome ( 12 - 28 ). A long survival was reported 17 cases.…”
The patient was a 39-year-old man hospitalized due to the presence of a cardiac mass and heart failure. Emergency tumor resection and mitral valve replacement were performed. The pathological findings of the tumor led to a diagnosis of cardiac leiomyosarcoma. After the operation, multiple metastases were found. The patient underwent three courses of chemotherapies: adriamycin, ifosfamide, dacarbazine, and mesna (MAID therapy), gemcitabine plus docetaxel, and sunitinib. During MAID therapy, the patient underwent resection of gastrointestinal metastases twice due to gastrointestinal hemorrhaging. Although he died 27 months after the initial treatment, use of multimodal therapy was effective in achieving a longer survival for the patient.
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