Primary Leiomyosarcoma of the Male Breast

Boehm, Daniel; Keller, K; Schmidt, Marcus; Cotarelo, Cristina; Kern, A; Lebrecht, Antje; Koelbl, Heinz

doi:10.4021/wjon238w

Cited by 2 publications

(3 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…SCP of the male breast are exceedingly rare, with the most common reported being myofibroblastoma 25 and fibromatosis, 26,27 in keeping with their frequency in our series. There are rare, published case reports of male breast phyllodes tumors, metaplastic carcinomas, and sarcomas 28–34 . No malignant SPC were represented in our series, and this was out of scope for this project.…”

Section: Discussionmentioning

confidence: 90%

See 1 more Smart Citation

Mammary Spindle Cell Proliferations on Core Needle Biopsy

Pun

Turashvili

Mulligan

et al. 2023

American Journal of Surgical Pathology

View full text Add to dashboard Cite

Mammary spindle cell proliferations (SCPs) encompass a wide range of lesions and can be challenging to accurately diagnose on core needle biopsies (CNBs). Most SCPs are excised for definitive diagnosis. In the era of minimally invasive therapy, some SCP may be followed conservatively. We aim to examine the spectrum of SCP diagnosed on CNB and evaluate if excision of benign/indeterminate SCP is always required. We identified patients with SCP across 3 institutions. The CNB were classified into benign, indeterminate, or malignant. Available excisional specimens were used to classify the lesion as benign or malignant. Clinical variables were reviewed. A total of 197 SCP met the inclusion criteria, including 100 (53%) CNB classified as benign, 52 (26%) indeterminate, and 36 (19%) malignant. Nine patients had excisions without a preceding CNB. Excision was performed in 47% of benign, 87% of indeterminate, and 86% malignant CNB. Of 123 excised SCP, 77 (63%) were benign, while 44 (36%) were malignant. Most benign lesions were not suspicious radiologically (67%), while indeterminate and malignant lesions were more likely to be suspicious (44% and 75%, respectively; P < 0.001). Malignant lesions tended to present as larger, rapidly growing, masses. Most mammary SCP are benign (63% of excisions). Appropriate ancillary tests can safely exclude some malignant entities. We encourage narrowing down the differential diagnosis to pertinent entities based on clinical presentation, imaging, histology, immunohistochemistry, and molecular studies, if applicable. Patients with mammary SCP may be spared surgery provided accurate pathologic diagnosis and appropriate correlation with imaging and clinical data.

show abstract

Section: Discussionmentioning

confidence: 90%

“…There are rare, published case reports of male breast phyllodes tumors, metaplastic carcinomas, and sarcomas. [28][29][30][31][32][33][34] No malignant SPC were represented in our series, and this was out of scope for this project.…”

Section: Discussionmentioning

confidence: 99%

Mammary Spindle Cell Proliferations on Core Needle Biopsy

Pun

Turashvili

Mulligan

et al. 2023

American Journal of Surgical Pathology

View full text Add to dashboard Cite

show abstract

“…We report a case of a primary leiomyosarcoma of the nipple which only accounts for less than 0.1% of all malignant neoplasms of the breast. Most patients are female, though there are at least four reported cases of male subjects with primary leiomyosarcoma of the breast [4]. It usually appears in postmenopausal women between the ages of fifty to eighty years and in some rare cases it can appear in young girls [5].…”

Section: Discussionmentioning

confidence: 99%

Primary leiomyosarcoma of the nipple-areola complex with an unusual clinical presentation: A case report

Guedes¹,

Medarde²,

Parra³

et al. 2014

IJCRI

View full text Add to dashboard Cite

International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations.IJCRI publishes Review Articles, Case Series, Case Reports, Case in Images, Clinical Images and Letters to Editor.

show abstract

Primary Leiomyosarcoma of the Male Breast

Cited by 2 publications

References 2 publications

Mammary Spindle Cell Proliferations on Core Needle Biopsy

Mammary Spindle Cell Proliferations on Core Needle Biopsy

Primary leiomyosarcoma of the nipple-areola complex with an unusual clinical presentation: A case report

Contact Info

Product

Resources

About