Primary liposarcoma of the mediastinum —A case report and review of the literature—

Abstract

Liposarcoma of the mediastinum is a rare disease. A 59 year old woman was seen with the complaint of dizziness. A chest radiogram taken during the course of investigation for hypertension revealed a large mass shadow 24 X 18.5 X 12 cm located in the anterior mediastinum. The tumor of the mediastinum was diagnosed as a benign lipoma when it was first resected, but subsequently proved to be a liposarcoma when it re-appeared 2 years and 10 month later. Based on the WHO classification, the mixed type of liposarcoma was diagnosed. The salient and pathological features of mediastinal liposarcoma are reviewed and compared with those nine cases reported in Japan and fifty in North America and European countries. Treatment by simple enucleation or shelling out of the tumor should be discouraged, since this seems to be the main cause of local recurrence. Surgical wide en bloc excision is the treatment of choice.

Multifocal extremity sarcoma: An uncommon and controversial entity

“…These factors allow us to more confidently compare time to metastasis and disease-free survival as a way to understand the biologic behavior of this entity. We have found that solitary extremity sarcoma has a 21% rate of pulmonary metastasis and a 75% 5-year survival, results that agree with previously reported series (8)(9)(10)(11)(12)(13). In contrast, patients with multifocal sarcoma have a 63% rate of pulmonary metastasis and only a 36% 5-year survival.…”

Successful Resection of a Primary Liposarcoma in the Anterior Mediastinum in a Child: Report of a Case

“…Shibata and coworkers reported an adult female case with a liposarcoma in whom a mediastinal lipoma had been extirpated. 11 They proposed that the tumor had either transformed from a lipoma or grew from the liposarcoma that had remained after the initial operation. Other investigators proposed myxoid and round cell types which originated from a white or brown adipose cell.…”

Successful Removal of a Posterior Cardiac Lipoma by Transection of the Ascending Aorta and Main Pulmonary Artery

“…Since lipomas are benign and the risk of recurrence is reported to be low [ 3 ], partial resection may be chosen if the risk of complications from tumor resection outweighs the risk of recurrence [ 5 ]. However, there are also reports of residual symptoms due to a remaining tumor and recurrence of a liposarcoma following partial resection [ 6 ], thus making complete resection desirable.…”