Primary lymphoma of the thyroid: Clinical features, prognostic factors, and results of treatment

Hodgkin's lymphoma of the thyroid: a clinicopathologic study of five cases and review of the literature

“…[14][15][16] Only rare cases of Hodgkin's lymphoma presenting in the thyroid have been reported in the literature. [17][18][19][20][21][22][23][24][25] Although it is controversial whether these cases represent primary thyroid Hodgkin's lymphoma or secondary thyroid involvement, the rarity of thyroid Hodgkin's lymphoma may lead to it being missed or not being considered in the differential diagnosis of a thyroid mass. Hodgkin's lymphoma presenting in the thyroid can mimic primary thyroid carcinoma or thyroiditis, producing diagnostic dilemmas.…”

Non-Hodgkin's Lymphomas (NHL)

“…A small, retrospective Swedish study showed that 5-year survival (75%) for irradiated patients was the same as in an age-matched normal population (129). A larger British study, however, found only 40"A~ 5-year survival, but many patients had received less than 40 Gy, and local relapse was 80% among these patients (130). A 5-year, relapse-free survival of 70% to 90% was reported in stage I. however, the recurrence rate was clearly higher in stage I1 (128,(131)(132)(133).…”

Autoimmune Disorders and Lymphomas

“…Complete surgical resection improves prognosis over incomplete resection, with a 5-year OS of 100% (Thieblemont et al, 2002), although most authors currently believe that total thyroidectomy is unnecessary, exposing patients to the risks of surgery (recurrent laryngeal nerve damage and hypoparathyroidism) without conferring any survival advantage (Tupchong et al, 1986, Ruggiero et al, 2005, Klyachkin et al, 1998. Involved field radiotherapy is associated with a 5-year OS of 90% (Laing et al, 1994).…”