Primary Malignant Cardiac Tumors: A Rare Disease With an Adventurous Journey

Gupta, Rajeev; Meghrajani, Vineet; Desai, Rupak; Gupta, Neelesh

doi:10.1161/jaha.120.016032

Cited by 25 publications

(34 citation statements)

References 18 publications

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“…Benign tumors are frequently cardiac myxomas and the rare primary malignant tumors are frequently sarcomas [ 16 , 17 ]. Intracardiac thrombi may develop secondary to acute myocardial infarction, or other underlying cardiac pathologies [4] .…”

Section: Discussionmentioning

confidence: 99%

Atypical imaging presentation of a massive intracavitary cardiac thrombus: A case report and brief review of the literature

Vasilakis

Lakhani

Adelanwa

et al. 2021

Radiology Case Reports

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Intracavitary cardiac thrombi, uncommonly found in the right chambers, have been shown to form secondary to endocardial and myocardial diseases. The differential diagnosis for an intracavitary cardiac mass is broad, including primary cardiac tumors, cardiac metastases, anatomic variants, vegetations, and thrombi. Here we present a unique case with a large calcified intracavitary cardiac thrombus in a 26-year-old woman with obesity, immune thrombocytopenic purpura, and a new diagnosis of systemic lupus erythematosus. Initial imaging presentation in this case masqueraded as a tumor, delaying the true diagnosis. A combination of cardiac imaging techniques, including transthoracic and transesophageal echocardiograms, cardiac CT, and cardiac MRI were required to correctly diagnose this calcified bland thrombus.

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Section: Discussionmentioning

confidence: 99%

Atypical imaging presentation of a massive intracavitary cardiac thrombus: A case report and brief review of the literature

Vasilakis

Lakhani

Adelanwa

et al. 2021

Radiology Case Reports

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show abstract

“…Approximately 20% of cardiac masses are malignant, including sarcoma, pericardial mesothelioma, primary lymphoma, and—most commonly—metastases (from either lung, breast, or hematologic cancer). 2 Cardiac sarcomas are the most common malignant primary cardiac tumours, arising from any chamber, but mostly from the right atrium. PAS is very rare, with approximately 400 cases reported since first described in 1923.…”

Section: Discussionmentioning

confidence: 99%

“… 4 Physical examination may show signs of right-ventricular failure. 2 Because of the nonspecificity of symptoms, a misdiagnosis of PE is common. Bandyopadhyay et al.…”

Section: Discussionmentioning

confidence: 99%

“…Other conditions that deserve consideration include obstructive pulmonary hypertension caused by a primary tumour into the pulmonary artery (PA), a cardiac lymphoma or metastases obstructing the right ventricular outflow tract. 1,2 A thoracic contrast-enhanced computer tomography (CT) was first ordered to exclude a PE. It showed a poly-lobulated 3.9 x 6.2 cm mass invading the pulmonary trunk.…”

Section: J O U R N a L P R E -P R O O Fmentioning

confidence: 99%

“…Other conditions that deserve consideration include obstructive pulmonary hypertension caused by a primary tumour into the pulmonary artery (PA), a cardiac lymphoma, or metastases obstructing the right ventricular outflow tract. 1 , 2 …”

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confidence: 99%

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Palpitations Revealing a Primary Pulmonary Artery Sarcoma

et al. 2021

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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A rare presentation of primary cardiac myxofibrosarcoma: Case report and literature review

Soltani,

Garousi,

Mirzaee

et al. 2024

Cancer Reports

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BackgroundPrimary cardiac myxofibrosarcoma is a rare and aggressive malignancy, with the majority of approaching strategies relying on case reports. This article provides insights into its diagnosis and treatment.Case PresentationThis paper presents the case of a 40‐year‐old man with sudden onset hemoptysis, leading to the diagnosis of primary cardiac myxofibrosarcoma. Treatment involved open‐heart surgery to excise the left atrium tumor, followed by 6 cycles of adjuvant chemotherapy. Unfortunately, brain metastasis developed, leading to the patient's death 1 year after initial diagnosis.ConclusionPrimary cardiac myxofibrosarcoma remains a clinical challenge with an unfavorable prognosis. Early diagnosis through advanced imaging is crucial, and research is needed to explore innovative treatments. This case underscores the complexities of managing this rare cardiac malignancy and highlights the necessity for ongoing investigations to enhance patient outcomes.

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Primary Malignant Cardiac Tumors: A Rare Disease With an Adventurous Journey

Cited by 25 publications

References 18 publications

Atypical imaging presentation of a massive intracavitary cardiac thrombus: A case report and brief review of the literature

Atypical imaging presentation of a massive intracavitary cardiac thrombus: A case report and brief review of the literature

Palpitations Revealing a Primary Pulmonary Artery Sarcoma

A rare presentation of primary cardiac myxofibrosarcoma: Case report and literature review

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