Primary Malignant Fibrous Histiocytoma of the Right Ventricle

Bălăceanu, Alice; D, Mateescu; Diaconu, Camelia Cristina; Sarsan, Adriana

doi:10.7863/jum.2010.29.4.655

Cited by 12 publications

(11 citation statements)

References 8 publications

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“…In our study, the median age in females was 56. 37 and was with 10% more in males. If we consider females and males combined the average age is 61-56 years despite that is 5-8 years higher like in other studies.…”

Section: Resultsmentioning

confidence: 85%

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Anaplastic Lymphoma Kinase (ALK) Overexpression in Lung Cancer Biopsies - An 18 month study in north western Romania

Pop¹,

Pusta²,

Buhaş³

et al. 2019

Rev. Chim.

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Lung cancer is the first cause of death worldwide of oncological patients. Most of them are non-small cell lung cancer (NSCLC) and many of them are characterized by different molecular markers that allow the development of personalized treatments. Epithelial growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) are the most frequently tested genes in lung adenocarcinoma and other lung carcinomas with glandular component. The aim of our study is to evaluate the distribution of ALK gene mutation in lung cancer patient from North West part of Romania. We analysed a number of 289 lung biopsies along 18 months. The samples have been incubated with monoclonal ALK antibodies (clone D5F3), according to the manufacturer�s instruction. The interpretation guide provided by manufacturer was used to distinguish the positives vs negative cases. In our study from a total number of 289 lung biopsies, 196 cases were carcinomas. 57.65 % from the total number of lung cancers were adenocarcinomas. A total number of 79 cases have been analysed for ALK gene supra expression. 5.08 % of adenocarcinomas were positive for ALK, but the mean age for this population is higher comparing with the data from other studies.

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Section: Resultsmentioning

confidence: 85%

“…Nowadays, it has been proved that ALK IHC is a better test compared to ALK FISH for predicting response to ALK inhibitors [35]. Patients with ALK IHC positive results have been responding to TKI therapy even when the FISH test was negative [36,37].…”

Section: Resultsmentioning

confidence: 99%

Anaplastic Lymphoma Kinase (ALK) Overexpression in Lung Cancer Biopsies - An 18 month study in north western Romania

Pop¹,

Pusta²,

Buhaş³

et al. 2019

Rev. Chim.

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“…It is well known and demonstrated by clinical and experimental studies that exposure to chemical substances also represent a risk factor for toxicity [11][12][13], or future development of tumors [14][15][16], in different organs like bladder, kidney etc [17][18][19][20], so a long follow up of the patients with self-injection should be required. In most of the cases the patients who practice illicit self-injection of those substances are young and they present to the doctor due to the complications that can appear during the following period (Table1).…”

Section: Resultsmentioning

confidence: 99%

Complications after Self-injection of Chemical Substances into the Penis

Martha¹,

Scarneciu²,

Scarneciu³

et al. 2019

Rev. Chim.

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Illicit injection of different, exogenous substances into the penis for enlargement purposes is a practice that is still met in some of the Eastern countries of Europe. Our study conducted over a period of 3 years (2016-2019) at the Urology Clinic from Tirgu Mures,highlights the complications that can occurre after the injection of different chemical substances, such as liquid paraffin, vaseline, olive oil etc., into the penile subcutaneous tissue with the purpose of augmentation. We report 7 patients presenting several complications some of them severe such as: extensive fibrosis, ulceration, penile deformity, erectile dysfunctions, requiring different surgical procedures. The surgical technique was selected according to the extension of fibrosis or necrosis:excision of the necrotic, fibrotic tissue, scrotal skin flap reconstruction etc. In our study, we found 7 patients that accomplished the inclusion criteria. Five patients were diagnosed with penile fibrosis after self-injection of Kanamycin, and two of the patients had the same diagnosis after self-injection of Vaseline. In 2 patients, the postoperative outcome was complicated by wound dehiscence and necrosis, requiring other reconstructive surgeries, and in 5 patients postoperative recovery was a favorable one, without significant complications. In the management of complications of illicit injection of different, exogenous substances into the penis, penile tunneling with scrotal flap technique seems to offer good results due to the vascular flap, allowing faster wound healing and a superior aesthetic and functional result.

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“…Malignant cardiac tumors are associated with a poor long-term survival despite surgery, radiotherapy and/or chemotherapy. [3] A few individual reports document complete recovery after successful removal of tumor with [6,7] or without [3] follow-up chemotherapy or radiotherapy. However, majority of the reported cases showed rapid progression, in terms of recurrence, local infiltration and distant metastasis, with clinical deterioration in a short time and eventual death.…”

Section: Discussionmentioning

confidence: 99%

Primary malignant fibrous histiocytoma involving the left pulmonary vein presenting as a left atrial tumor

Bandyopadhyay¹,

Banerjee²,

Paul³

et al. 2013

Ann Card Anaesth

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A 35-year-old woman presented with 4 months history of progressively increasing intermittent dyspnea and hemoptysis. Transthoracic echocardiography revealed a loculated mass in the left atrium (LA). A provisional diagnosis of LA myxoma was made. Intraoperatively the tumor was found extending into and closely adherent to the left pulmonary vein and could not be completely cleared off from the pulmonary venous wall. The histopathological examination of the tumor revealed it to be a myxoid malignant fibrous histiocytoma.

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Primary Malignant Fibrous Histiocytoma of the Right Ventricle

Cited by 12 publications

References 8 publications

Anaplastic Lymphoma Kinase (ALK) Overexpression in Lung Cancer Biopsies - An 18 month study in north western Romania

Anaplastic Lymphoma Kinase (ALK) Overexpression in Lung Cancer Biopsies - An 18 month study in north western Romania

Complications after Self-injection of Chemical Substances into the Penis

Primary malignant fibrous histiocytoma involving the left pulmonary vein presenting as a left atrial tumor

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