Primary malignant melanoma of the common bile duct: a case report and literature review

González, Natalia Bejarano; Moforte, N. García; Martín, Álvarez; Fernandez, Martin; Rosello, Esther; Soto, Salvador Navarro

doi:10.1157/13077759

Cited by 11 publications

(7 citation statements)

References 9 publications

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“…The youngest case reported was a 26-year-old man, but had the best disease-free survival of 6 years. 19 The most common presentation is cholestatic jaundice (in 7/12 patients), as was the case with our patient, followed by abdominal pain/discomfort, 9 , 13 , 19 diffuse pruritus, 15 and acute cholecystitis. 11 Diagnosis of PMM-BD needs a high index of suspicion and may employ several diagnostic modalities, including ultrasonogram, computed tomography, or MRI/MRCP to demonstrate biliary obstruction and exclude pancreatic/ampullary pathologies.…”

Section: Discussionsupporting

confidence: 80%

Primary Bile Duct Melanoma Causing Obstructive Jaundice

Addepally

Klair

Lai

et al. 2016

ACG Case Reports Journal

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Malignant melanoma is one of the few malignancies that are well known for unusual behavior. Primary malignant melanoma usually originates from squamous epithelium of skin, mucous membranes, retina, and uvea. Although melanoma can metastasize to any part of the body, including biliary tract, primary malignant melanoma of bile ducts is an extremely rare entity. We present a 52-year-old man who presented with 5-month epigastric pain and 15-pound weight loss, with 1-week duration of jaundice, nausea/vomiting, pale stools, and dark urine, blood work suggested cholestatic jaundice. Imaging revealed a large perihilar/peripancreatic mass involving the portal vein and hepatic artery, and intrahepatic biliary dilation. Biliary brushings revealed neoplastic cells strongly suggestive of malignant melanoma.

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Section: Discussionsupporting

confidence: 80%

Primary Bile Duct Melanoma Causing Obstructive Jaundice

Addepally

Klair

Lai

et al. 2016

ACG Case Reports Journal

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“…Our research revealed that less than 20 cases of metastatic melanoma involving the common biliary duct have so far been reported in the English literature 3–5 . In the literature, in addition to cases of metastatic MM of the common bile duct, those with primary MM have also been described 6 . A comprehensive physical search to rule out other locations of primary malignancy is required for this diagnosis.…”

mentioning

confidence: 77%

Metastatic melanoma of the common bile duct diagnosed with brush cytology

Rezanko¹,

Bolat²,

Gelal³

et al. 2007

Cytopathology

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“…The most frequent sites of metastasis are the liver, lungs, and brain 2,45 . Spread to the gastrointestinal tract is found in 2%–4% of patients 3 . Mostly, it affects the small bowel (35%–67%), colon (9%–15%), and stomach (5%–7%) 2,4 .…”

Section: Discussionmentioning

confidence: 99%

“…In these cases, open cholecystectomy followed by partial V‐segmentectomy is performed. Although an open approach is often preferable, 3 laparoscopic dissection, when executed by an experienced surgeon, is an adequate and highly efficient method. Statistically, there was no significant difference between histological layer infiltration and the preferred procedure (Sig = 0.132, H = 5.73).…”

Section: Discussionmentioning

confidence: 99%

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Role of minimally invasive surgery in the treatment of gallbladder metastatic melanoma. A review of the literature and a case report

et al. 2022

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Background: Primary and secondary gallbladder melanomas are rare, and only 58 cases have been reported in scientific literature to date. This paper aimed to explore the role of minimally invasive surgery in the management of gallbladder metastatic melanomas.Case: Herein, we present the case of a 68-year-old man with metastatic gallbladder melanoma who was treated with laparoscopic cholecystectomy. Our case management was then compared with that of other cases reported in the literature. Conclusion:Currently, metastatic melanomas can be considered as a potentially curable disease. Palliation of symptoms and fast recovery following minimally invasive procedures could be beneficial for these patients. Particularly, laparoscopic procedures appear to prolong the survival of gallbladder melanoma patients.

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Primary malignant melanoma of the common bile duct: a case report and literature review

Cited by 11 publications

References 9 publications

Primary Bile Duct Melanoma Causing Obstructive Jaundice

Primary Bile Duct Melanoma Causing Obstructive Jaundice

Metastatic melanoma of the common bile duct diagnosed with brush cytology

Role of minimally invasive surgery in the treatment of gallbladder metastatic melanoma. A review of the literature and a case report

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