Primary malignant melanoma of the vagina in a postmenopausal woman

Ahn, Hee Young; Park, Jin Wan; Kim, Jong Soo

doi:10.21767/amj.2017.3296

Cited by 2 publications

(1 citation statement)

References 17 publications

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“…Akan tetapi, ukuran tumor dapat digunakan untuk memprediksi kesintasan hidup. 18,19 Tabel 3. Klasifikasi stadium menur ut FIGO dan sistem TNM (AJCC 8 th ) 19…”

Section: Gejala Klinis Dan Diagnosisunclassified

Melanoma Maligna Vagina: Laporan Kasus dan Tinjauan Literatur

Kristian¹,

Supriana²

2020

Radioter Onkol Indones

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Melanoma maligna vagina adalah salah satu melanoma mukosa ganas yang sangat jarang, bersifat agresif dan memberikan prognosis yang buruk dengan angka kesintasan 5 tahun yang rendah. Hingga saat ini belum ada pedoman yang jelas mengenai tatalaksana penyakit ini. Penanganan multidisplin berupa pembedahan, kemoterapi, radiasi hingga immunoterapi, masih belum memberikan hasil yang baik. Meskipun sifatnya dikenal sebagai tumor yang radioresisten, beberapa bukti memperlihatkan bahwa radioterapi ajuvan pasca operasi dapat meningkatkan kontrol lokal tumor. Kami melaporkan kasus melanoma maligna vagina yang mendapat radiasi definitif tanpa pembedahan

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“…Akan tetapi, ukuran tumor dapat digunakan untuk memprediksi kesintasan hidup. 18,19 Tabel 3. Klasifikasi stadium menur ut FIGO dan sistem TNM (AJCC 8 th ) 19…”

Section: Gejala Klinis Dan Diagnosisunclassified

Melanoma Maligna Vagina: Laporan Kasus dan Tinjauan Literatur

Kristian¹,

Supriana²

2020

Radioter Onkol Indones

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Survival and Treatment Modalities in Primary Vaginal Melanoma—Case Report and a Narrative Review

Guzik,

Łukasiewicz,

Harpula

et al. 2024

JCM

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Background/Objectives: Primary vaginal melanoma (PVM) is a rare cancer representing five percent of vaginal cancers and less than one percent of all female vaginal melanomas, with an incidence rate of 0.46 per million women per year. The aim of this study was to present a case of combined therapy and conservative surgical treatment in a young patient with PVM and to perform a systematic review of the same subject. Methods: We performed a narrative review of the literature and presented a case report. Results: The review yielded a total of 43 articles. We presented treatment modalities and survival outcomes. The presented case involved a combination of surgical treatment with adjuvant therapy comprising nivolumab and ipilimumab. Conclusions: PVM is a disease with a poor prognosis; however, new treatment options are promising and have a great chance of significantly improving survival. The combination of the wide local excision of the primary lesion followed by adjuvant therapies results in the best outcomes in the treatment of PVM. Future clinical studies are warranted to provide new evidence for the treatment outcomes of nonsurgical, metastatic PVM and the adjuvant treatment of PVM.

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Primary malignant melanoma of the vagina in a postmenopausal woman

Cited by 2 publications

References 17 publications

Melanoma Maligna Vagina: Laporan Kasus dan Tinjauan Literatur

Melanoma Maligna Vagina: Laporan Kasus dan Tinjauan Literatur

Survival and Treatment Modalities in Primary Vaginal Melanoma—Case Report and a Narrative Review

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