Primary malignant tumors of the hand

Adeyemi-Doro, H. Olusanya; Durosimi-Etti, F.A.; Olude, O.

doi:10.1016/s0363-5023(85)80156-8

Cited by 8 publications

(1 citation statement)

References 4 publications

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“…Although these tumors are rare, they can be locally aggressive and tend to have a poor prognosis 112 . Rates of metastases remain unknown, although a number of case reports describe lung, myocardial, and most commonly lymph node metastases 113–116 . These tumors tend to have a high rate of local recurrence 116,117 …”

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confidence: 99%

Soft Tissue Tumors of the Hand. 2. Malignant

et al. 2007

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Soft tissue tumors of the hand arise from skin, subcutaneous tissue, tendons, nerve, and blood vessels. Many of these lesions occur on other parts of the body; however, the hand remains a unique site because these tumors have symptoms, appearances, treatments, and prognoses that may be quite different than when on other parts of the body. Their characteristics and the severity of symptoms vary markedly depending on the exact location, size, and type of tumor-and many of these tumors can have multiple forms of presentation. Two articles are intended to provide an overview of benign (previous article) and malignant tumors (this article) of the hand. The rarer and more deleterious tumors are discussed in detail while the common tumors and epidermal lesions with which practitioners are familiar are briefly overviewed. At the completion of these review articles, participants should be able to identify and diagnose various benign and malignant hand tumors as well as understand the accepted current treatment of these growths.

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confidence: 99%

Soft Tissue Tumors of the Hand. 2. Malignant

et al. 2007

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Metastasis of Epithelial Neoplasms: Desmal Epithelia (Including Vasoformative Tissue), Epithelia of Synovial Origin

Kaiser¹

1989

Metastasis / Dissemination

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Rhabdomyosarcoma Arising in the Hand or Foot: A Clinicopathologic Analysis

2004

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Rhabdomyosarcomas (RMS) arising at different anatomic sites have distinct clinicopathologic features that affect prognosis and outcome. RMS arising in the extremities generally have a worse prognosis. Case reports and anecdotal experience suggests the possibility that RMS of the hand or foot (RMSHF) may behave even more aggressively than RMS elsewhere in the extremities. This study describes clinicopathologic features and outcome of RMSHF. Charts and pathologic material from RMSHF cases from institutional files over a 32-year interval were reviewed. Additional cases from published reports and series over a 42-year interval were identified by a MEDLINE search. Pertinent clinicopathologic features for each case were compiled. Survival analysis and other data from these patients were compared with previously reported statistics in the literature for RMS at other anatomic sites, including elsewhere in the extremities. Six patients from the institutional files and 46 from published reports were identified. A number of adverse prognostic indicators were observed in the majority of these patients including alveolar morphology (86%) and distant metastasis at presentation (63%). Despite the aggressive nature of these tumors, the majority were smaller than 5 cm (61%). A propensity was observed for metastases to unusual sites such as breast, ovary, testis, pancreas, and kidney. The median survival was 19 months, and the 5-year survival was 27%. While these may reflect a constellation of findings related to site, it is also possible that alveolar histology is the main influence. RMSHF can present as a very small primary tumor with clinically evident or occult metastatic disease. Whether this reflects the location, the predominantly alveolar histologic type, or a molecular genetic subtype will require further analysis. Patients presenting with RMSHF should be thoroughly evaluated for occult metastases at the time of diagnosis and followed closely throughout treatment for subsequent involvement of unusual sites.

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Primary malignant tumors of the hand

Cited by 8 publications

References 4 publications

Soft Tissue Tumors of the Hand. 2. Malignant

Soft Tissue Tumors of the Hand. 2. Malignant

Metastasis of Epithelial Neoplasms: Desmal Epithelia (Including Vasoformative Tissue), Epithelia of Synovial Origin

Rhabdomyosarcoma Arising in the Hand or Foot: A Clinicopathologic Analysis

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