Primary MALToma of the Prostate.

Abstract

To Editor, Mucosa-associated lymphoid tissue (MALT) lymphoma is a distinct disease with specific clinical and pathologic features that may affect diverse organs. MALT lymphoma of the prostate is rare, and only eight cases have been reported in the literature.A 48-year-old male patient presented with urinary obstruction, pollacuria, and the sensation of burning during urination. Physical examination was normal, except for an enlarged prostate. CTs of the neck, thorax, and upper abdomen were normal, but lower abdominal CT confirmed the enlarged prostate. Serum prostate-specific antigen (PSA) level was 0.38 ng mL -1 (normal: <4 ng mL -1 ) and urological evaluation revealed lower urinary tract obstruction. The patient underwent transurethral resection (TUR) of prostate with the diagnosis of lower urinary tract obstruction. The morphology and immunohistochemical staining of the prostatic specimen were in accordance with marginal zone lymphoma and the patient was diagnosed as the mature small B-cell lymphoid neoplasm of the prostate.

A case of recurrent hematuria in primary prostatic low grade mucosa associated lymphoid tissue

“…But it seems that these prostatic MALTomas have an indolent growth with a good prognosis (8,10). According to the published reports, prostatic MALTomas are mainly presented with urinary obstruction, or hematuria.…”

“…Low-grade marginal zone lymphomas are composed of multifocal proliferations of polymorphous lymphoid cells including small lymphocytes with dark round nuclei, small lymphocytes with irregular nuclear contours and pale cytoplasm. For distinguishing reactive follicles from follicles invaded by lymphoma, immunhistochemical determination of the number and distribution of CD20-positive B cells and CD3-positive T cells may be useful ( 10 ).…”

“…As mentioned before these kinds of tumors are very rare and the 10 previously reported cases in the literature are not enough to certainly discuss about the best treatment option and prognosis. But it seems that these prostatic MALTomas have an indolent growth with a good prognosis ( 8 , 10 ). According to the published reports, prostatic MALTomas are mainly presented with urinary obstruction, or hematuria.…”

“…According to the published reports, prostatic MALTomas are mainly presented with urinary obstruction, or hematuria. Chemotherapy, transurethral resection, and external radiotherapy are successfully applied treatment options ( 1 - 10 ).…”