Primary Mature Cystıc Teratoma Mimickıng an Adrenal Mass in an Adult Male Patient

Okulu, Emrah; Ener, Kemal; Aldemir, Mustafa; Işık, Evren; Irkkan, Çiğdem; Kayıgίl, Önder

doi:10.4111/kju.2014.55.2.148

Cited by 11 publications

(8 citation statements)

References 8 publications

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“…[ 10 ] The malignancy rate of 25.8% in adults is significantly higher than 6.8% rate documented in children. [ 11 12 ] Surgical excision is the method of choice for the diagnosis as well as treatment of the mature teratoma. [ 11 ] We did open transperitoneal adrenalectomy in view of large size (20 cm) and suspicion of malignancy.…”

Section: Discussionmentioning

confidence: 99%

Primary adrenal teratoma

Ramakant

Rana

Singh

et al. 2018

Journal of Postgraduate Medicine

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We report a rare case of a 25-year-old lady who presented with right hypochondriac pain associated with weakness for 3 months. Her hormonal evaluation was normal. Computed tomography scan revealed an adrenal mass for which a right open transperitoneal adrenalectomy was performed, and the lesion was diagnosed as mature teratoma on histopathological examination. Teratoma is an unusual neoplasm which arises from one or all the three germ layers. Extragonadal teratomas are rare in adults as compared to children and are mostly retroperitoneal in location, constituting only 4% of all primary teratomas. Primary adrenal teratomas are even rarer and to the best of our knowledge, only eight cases have been reported in adults in the past 10 years. Adrenal teratoma can pose a diagnostic challenge because radiologically it mimics myelolipoma, angiomyolipoma, liposarcoma, or pheochromocytoma. Mature teratomas are usually benign but may possess malignant potential, the chances of which are greater in adults as compared to children, making it an important entity requiring a proper diagnosis and management.

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Section: Discussionmentioning

confidence: 99%

Primary adrenal teratoma

Ramakant

Rana

Singh

et al. 2018

Journal of Postgraduate Medicine

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“…6 , 14 , 46 – 49 The most recent report was on a 54-year-old male with a left suprarenal mass presenting as left upper quadrant abdominal and flank pain. 50 …”

Section: Discussionmentioning

confidence: 99%

Primary retroperitoneal mature cystic teratoma (dermoid cyst) in a 51-year-old male:Case report and historical literature review

Tiu

Sovani

Khan

et al. 2017

SAGE Open Medical Case Reports

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Objectives:Primary retroperitoneal mature cystic teratomas are exceedingly uncommon in males aged 50 years and above, and only seven cases have been reported in the literature so far. They usually occur in infants less than 6 months and young females. The aim of this article is to present a rare case of a 51-year-old male with a primary retroperitoneal mature cystic teratoma located in the right infrarenal area adherent to the psoas muscle and to discuss a historical literature review.Methods:An incidental hypoechoic, solid appearing 8.2 × 7.6 × 7.8 cm3 mass arising off the inferior pole of the right kidney was found on abdominal ultrasound during evaluation for a history of alcoholism. Computerized tomography (CT) scan revealed small calcifications in the lower part of the cystic mass. Laparotomy with excision of the retroperitoneal mass was performed.Results:On gross examination, the specimen consisted of a cyst filled with pale yellow greasy material with entrapped hair. Histopathologic examination revealed a dermoid cyst with focal chronic inflammation, dystrophic calcification, and foreign-body giant cell reaction.Conclusions:Retroperitoneal mature cystic teratoma in an older male is extremely rare. Primary gonadal teratoma with retroperitoneal metastasis should be excluded first. Evaluation of age and location of tumor are critical for its prognosis. Complete excision of tumor is necessary to evaluate whether there are immature and solid elements which need long-term follow up due to the increased risk of malignancy.

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“…Only 10-20% of them occur in adults more than 30 years of age (7). Retroperitoneal ones were usually misdiagnosed as adrenal tumors (11)(12)(13), pancreatic cysts (14), gastric stromal tumor (15) and so on. The majority of cases were asymptomatic (8,14), and the most common symptom was nonspecific pain (7,16).…”

Section: Clinical Features Of Retroperitoneal Dermoid Cystmentioning

confidence: 99%

“…Patients whose adrenals were compressed might be present with vertigo and hypertension (13,16), making the diagnosis more confusing. The incidence of malignant transformation is approximately 3-6% (12). Besides squamous cell carcinoma which accounts for 75-87% (17), enteric differentiation (11), mucinous adenocarcinoma (18), sarcoma, melanoma (9) and ganglion neuroblastoma (16) were also reported.…”

Section: Clinical Features Of Retroperitoneal Dermoid Cystmentioning

confidence: 99%

“…However, there are no skin appendages such as sebaceous glands, hair follicles, and hair only in epidermoid cyst. For mature cystic teratomas and dermoid cysts, the former contains at least two germ cell layers with a common appearance of calcification (12,14,17), while the latter is a single layer with rare calcification (7) and no scolex (1). Both of them are mainly composed of skin and skin appendages, so many clinicians used " mature cystic teratomas" to call them both (10-13) (Table 1).…”

Section: Histopathological Analysis Of Dermoid Cyst and The Differential Diagnosesmentioning

confidence: 99%

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Retroperitoneal dermoid cyst mimicking a liposarcoma based on imaging assessment: case report and literature review

Ma¹,

Xiao²,

Wang³

2021

Gland Surg

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Dermoid cyst is a kind of mature cystic teratoma that contains only one germ layer. It usually occurs in the head and neck, retroperitoneal dermoid cysts are uncommon. Teratomas are characterized by mixed density and features like calcification or air-fluid level. Here, we present a case of 40-year-old female with a 12.1 cm × 10.0 cm retroperitoneal fatty mass which showed no calcification and few other specific characteristics of teratoma. Thin and uniform separations were observed. On PET-CT, it was adherent to several retroperitoneal organs like left adrenal gland and left kidney, and had a close relationship with several retroperitoneal vessels like aorta, superior mesenteric arteriovenous, left superior renal artery and inferior vena cava. On PET-CT, mild 18F-FDG uptake was observed. Based on the above imaging findings, a clinical diagnosis of liposarcoma was considered. After laparotomy and open surgery transit through a left vertical incision, the histopathologic examination revealed a retroperitoneal dermoid cyst. During a 2-month followup, the patient recovered well without discomfort and recurrence. Comparison between dermoid cyst and liposarcoma in imaging findings was performed. In dermoid cysts, there can be thin and uniform separations, rather than linear, localized and irregular high density in liposarcoma. The difference between dermoid cyst and mature cystic teratoma is yet to be clarified. A review of clinical and histopathological features of retroperitoneal dermoid cyst was also performed to enhance the level of the diagnosis and management.

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Primary Mature Cystıc Teratoma Mimickıng an Adrenal Mass in an Adult Male Patient

Cited by 11 publications

References 8 publications

Primary adrenal teratoma

Primary adrenal teratoma

Primary retroperitoneal mature cystic teratoma (dermoid cyst) in a 51-year-old male:Case report and historical literature review

Retroperitoneal dermoid cyst mimicking a liposarcoma based on imaging assessment: case report and literature review

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