Primary Melanoma of the Spinal Cord

Kiel, Frank W.; Starr, Leonard B.; Hansen, James L.

doi:10.3171/jns.1961.18.5.0616

Cited by 71 publications

(29 citation statements)

References 26 publications

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“…It appears that primary dural melanoma follows a less aggressive course with patients surviving longer than those with leptomeningeal melanoma. 15, 45 Kiel et al 48 reviewed leptomeningeal melanoma and showed a median postoperative survival of 1 month and an overall 2-year survival of only 15%. Patients treated surgically for primary dural melanoma and dural melanoma associated with Nevus of Ota fare somewhat better 4,10,15 : disease-free intervals range from 9 to 18 months after treatment for the former, and the median postoperative survival was 4 years for the latter.…”

Section: Discussionmentioning

confidence: 97%

Dural Melanoma Associated with Ocular Melanosis and Multiple Blue Nevi

Rivers

Bhayana

Martinka

2001

Journal of Cutaneous Medicine and Surgery: Incorporating Medical and Surgical Dermatology

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Section: Discussionmentioning

confidence: 97%

Dural Melanoma Associated with Ocular Melanosis and Multiple Blue Nevi

Rivers

Bhayana

Martinka

2001

Journal of Cutaneous Medicine and Surgery: Incorporating Medical and Surgical Dermatology

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“…Most of the cases of CNS melanin bearing tumours are metastatic melanomas constituting 3-16% of secondary neoplastic foci in CNS, melanotic neurocutaneous syndromes and primary leptomeningeal melanoma. [8,9] Primary melanocytic neoplasms arise from normally occurring leptomeningeal melanocytes which are derived from the neural crest during early embryonic development. [10] Normal rests of pigmented cells within the CNS include the medulla, pons, substantia nigra, locus cerulus and the leptomeninges over the convexities, basal region and upper cervical spinal cord.…”

Section: Discussionmentioning

confidence: 99%

Primary CNS Melanoma in an Albino: A Rare Case Report

Kishore¹,

Bhardwaj²,

Mohit³

et al. 2014

jemds

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Primary intracranial melanoma is a rare and uncommon lesion. Association of primary CNS melanoma in an albino has not been reported in literature searched till now. We are presenting a rare case of primary CNS melanoma in a 52years old male with occulocutaneous albinism. The patient presented with repeated episodes of generalized headache, vomiting and ataxia for duration of 5months. MRI examination showed a tumor in the posterior fossa that was diagnosed as Ependymoma radiologically. Surgical treatment with total removal of tumor was done. Intraoperative squash cytology and frozen section followed by histopathology confirmed the diagnosis of Melanoma. A thorough investigation of the patient was performed including chest radiography, ocular examination, ultrasonography of abdomen and barium enema to rule out any other site of primary melanoma in the body. Thus a final diagnosis of primary CNS melanoma was given.

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“…With aggressive intervention, patients with primary CNS melanoma survive, on average, 5 months (metastatic CNS melanoma patients average 11.5 months with response to initial treatment [16, 31]).…”

Section: Discussionmentioning

confidence: 99%

Primary Pineal Malignant Melanoma

Bookland

Anderson²,

Biser-Rohrbaugh

et al. 2007

Pediatr Neurosurg

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Primary pineal malignant melanomas are a rare subset of primary central nervous system melanomas. This report presents the case of a 20-year-old female patient with a primary pineal region malignant melanoma who underwent endoscopic biopsy and adjuvant therapy. Her treatment consisted of stereotactic radiation to the pineal tumor, conventional whole-brain radiation and Temodar® for the disseminated disease. She required a ventriculo-peritoneal shunt for refractory ICP problems. This report details the clinical features of the case and summarizes the literature on a rare but aggressive neoplasm.

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Primary Melanoma of the Spinal Cord

Cited by 71 publications

References 26 publications

Dural Melanoma Associated with Ocular Melanosis and Multiple Blue Nevi

Dural Melanoma Associated with Ocular Melanosis and Multiple Blue Nevi

Primary CNS Melanoma in an Albino: A Rare Case Report

Primary Pineal Malignant Melanoma

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