Primary Mesenchymoma of the Pulmonary Artery: Radiological Features

Ante mortem Diagnosis of Primary Leiomyosarcoma of the Pulmonary Artery

“…Likewise, radio logical signs (in particular angiopneumog raphy) could only create a suspicion of the disease. In fact, radiological differentia tion between an occlusion of a pulmonary artery due to thromboembolism and an obliterating tumor will always be prob lematic [4], It is thought that small tumor cells, rich in tissue thromboplastin, enter the pulmonary circulation and give rise to intravascular coagulation of the pulmo nary vessels [5], The symptomatology of chest pain, hemoptysis, febrile episodes and the presence of fibrosclerotic stria in the right lower lobe on the chest x-ray sug gested the diagnosis of thromboembolic disease. We, therefore, started to treat the patient with an anticoagulant therapy.…”

“…From a review of similar cases, leiomyo sarcoma of the pulmonary arterial vessels is often clinically confused with thrombo embolic disease [4], Thus, the clinician should always consider a vascular leiomyo sarcoma in the presence of nonembolic obstruction of the pulmonary vessels in the hope of achieving an earlier diagnosis and possibly a surgical cure.…”

Primary Leiomyosarcoma of the Pulmonary Artery

“…Different histologic classifications of this tumor have been proposed [9], such as spindle cell sar coma, fibrosarcoma, leiomyosarcoma, ma lignant mesenchymoma, myoplastic sarcoma with giant cells, rhabdomyosarcoma, intimal sarcoma of Hedenger and anaplastic sarcoma. A simple classification [8] is based on the relative amount of fibrous and muscu lar tissue present in the tumor, hence the names fibrosarcoma [18, 28,30] or leiomyo sarcoma [20, 30. 39], In the cases reported so far, a specific etiologic factor could not be discovered.…”

Spindle cell sarcoma of the pulmonary trunk: A case report with histochemistry and electron microscopy

“…In descriptions of the microscopy of the tumour in previous cases, a variety of cell types have been described (Durgin et al, 1946;Elphinstone et al, 1959;Wolf et al, 1960;Hagstrom, 1961;Munk et a/., 1965) varying in different areas of the neoplasm: primitive cartilage, bony trabeculae and spindle cells resembling fibroblasts. Some cells contained intracytoplasmic fibrils (Durgin et al, 1946;Friedman et al, 1968).…”