Primary Mesenteritis, Mesenteric Fibrosis and Mesenteric Fibromatosis

Remmele, W.; Müller-Lobeck, H; Paulus, Werner

doi:10.1016/s0344-0338(88)80194-8

Cited by 14 publications

(8 citation statements)

References 29 publications

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“…Mindelzun et al [8] have coined the term of 'misty mesentery' to describe the appearance of altered mesenteric fat on computed tomography (CT) [8]. Mesenteric abnormalities as diagnosed by CT scans have further been described as 'primary (idiopathic) mesenteritis' [11], 'mesenteric lipodystrophy' [12,13], 'retractile mesenteritis' [14][15][16][17], 'intraabdominal panniculitis' [18], 'mesenteric panniculitis' [9,19,20], or 'sclerosing mesenteritis' [21] among others. With infiltration of the mesentery by fluid or cells, the mean density of mesenteric fat increases to -28 to -85 Hounsfield Units, and the mesenteric arteries and veins often lose their sharp interfaces [9].…”

Section: Introductionmentioning

confidence: 99%

CT-Diagnosed Mesenteric Alterations in Patients with Non-Hodgkin’s Lymphoma: A Population-Based Study

Joerger¹,

Nuessli²,

Henz³

et al. 2008

Onkologie

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Background: Mesenteric alterations are associated with non-Hodgkin’s lymphoma (NHL), but the frequency and prognostic value of mesenteric alterations are unknown in patients with NHL. Patients and Methods: We retrospectively screened 120 patients that were treated for NHL between January 1996 and December 2001 for the presence of mesenteric alterations, defined on computed tomography (CT) scans as nodular or diffuse infiltration of the abdominal mesentery with increased density of mesenteric fat. Results: 21 patients (17.5%) had radiological findings of mesenteric alterations at the time of the initial NHL diagnosis. Mesenteric alterations were significantly associated with mesenteric lymphadenopathy (p = 0.01). In about 50% of the patients, mesenteric alterations could not be explained by direct mesenteric tumour invasion or overt lymphatic obstruction. Patients with initial findings of mesenteric alterations tended to have a better 4-year survival as compared to patients without such findings (79 vs. 43%, p = 0.11). The International Prognostic Index (IPI) score was the only independent predictor of survival in the multivariate analysis. Conclusion: This retrospective screening study found a moderate prevalence of mesenteric alterations in patients with various subtypes of NHL. The diagnostic and prognostic value of mesenteric alterations should be further assessed in prospective studies.

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Section: Introductionmentioning

confidence: 99%

CT-Diagnosed Mesenteric Alterations in Patients with Non-Hodgkin’s Lymphoma: A Population-Based Study

Joerger¹,

Nuessli²,

Henz³

et al. 2008

Onkologie

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“…Intra-adominal panniculitis is a tumour-like inflammatory condition of adipose tissue. About 300 cases have been described, but it is difficult to get a comprehensive view because of the great number of terms used 1,2 . Most cases are located in the small bowel mesentery, but any fat-containing region in the abdomen can be involved 3 .…”

Section: Introductionmentioning

confidence: 99%

Nodular intra‐abdominal panniculitis: an accompaniment of colorectal carcinoma and diverticular disease

Bak

1996

Histopathology

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Intra-abdominal panniculitis is a tumour-like inflammatory condition of adipose tissue. The aetiology and pathogenesis of the disease is unknown, but a number of associated diseases have been recorded. It has been customary to deal with only primary cases in the literature. This study was undertaken in order to describe the entire spectrum of the disease including primary as well as secondary cases. Eleven patients are reported, nine of which had an associated colorectal disease in direct continuity with areas of intra-abdominal panniculitis. It is concluded that intra-abdominal panniculitis should not be regarded as a specific nosological entity but merely a result of injury to the fat cells. Intra-abdominal panniculitis is seen more often as a secondary local phenomenon than as a primary condition, and in both cases it is associated with considerable differential diagnostic problems. Primary diseases involved are, among others, colorectal carcinoma and diverticulosis. The aetiologic agent(s) are still unknown, but substances liberated from a damaged bowel might play a pathogenetic role.

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“…It is generally regarded as a chronic inflammatory and/or sclerotic disease entity of lymphoreticular origin. The clinical characteristics, histological descriptions, and pathogenesis are beyond the scope of this text and are reviewed elsewhere [1,2], An increased incidence of malignant lymphoma has been reported in a review of 53 patients with mesenteric lipodystrophy [3], This observa tion is quite interesting especially in light of the welldescribed association between minimal change nephropa thy and Hodgkin's lymphoma [4]. We describe a patient with an 18-month history of sclerosing mesenteritis who developed the nephrotic syndrome with classical histolog ical features of minimal change nephropathy.…”

Section: Introductionmentioning

confidence: 99%

Minimal Change Nephropathy Associated with Sclerosing Mesenteritis

Ag²,

Rt³

et al. 1996

Nephron

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A 65-year-old man with sclerosing mesenteritis developed the nephrotic syndrome. Percutaneous renal biopsy revealed classical histologic findings of minimal change nephropathy with a mild interstitial nephritis. Immunomodulation with prednisone led to a rapid and complete remission of the proteinuria but did not alter the course of the underlying sclerosing mesenteritis. The association of lymphomatous and nonlymphomatous neoplasms with minimal change nephropathy has been well-described. Our review of the literature indicates a parallel association of malignant lymphoma with sclerosing mesenteritis and a variety of disorders that constitute a spectrum of disease. The occurrence of this histopathologic form of renal injury and therapeutic response in the setting of a known lymphoreticular disorder suggests a role for a generalized alteration in cell-mediated immunity and not a tumor-induced elaboration of a factor(s) that directly damages the glomerular filtration barrier.

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Primary Mesenteritis, Mesenteric Fibrosis and Mesenteric Fibromatosis

Cited by 14 publications

References 29 publications

CT-Diagnosed Mesenteric Alterations in Patients with Non-Hodgkin’s Lymphoma: A Population-Based Study

CT-Diagnosed Mesenteric Alterations in Patients with Non-Hodgkin’s Lymphoma: A Population-Based Study

Nodular intra‐abdominal panniculitis: an accompaniment of colorectal carcinoma and diverticular disease

Minimal Change Nephropathy Associated with Sclerosing Mesenteritis

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Primary Mesenteritis, Mesenteric Fibrosis and Mesenteric Fibromatosis

Cited by 14 publications

References 29 publications

CT-Diagnosed Mesenteric Alterations in Patients with Non-Hodgkin&rsquo;s Lymphoma: A Population-Based Study

CT-Diagnosed Mesenteric Alterations in Patients with Non-Hodgkin&rsquo;s Lymphoma: A Population-Based Study

Nodular intra‐abdominal panniculitis: an accompaniment of colorectal carcinoma and diverticular disease

Minimal Change Nephropathy Associated with Sclerosing Mesenteritis

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Product

Resources

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CT-Diagnosed Mesenteric Alterations in Patients with Non-Hodgkin’s Lymphoma: A Population-Based Study

CT-Diagnosed Mesenteric Alterations in Patients with Non-Hodgkin’s Lymphoma: A Population-Based Study