2009
DOI: 10.1007/s00423-008-0453-9
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Primary mesh augmentation with fibrin glue for abdominal wall closure—investigations on a biomechanical model

Abstract: The prophylactic use of meshes for stabilization of laparotomy closures appears to be effective. Adequate mesh fixation can be achieved with fibrin glue alone. Further experimental studies and in particular randomized clinical trials are needed to demonstrate proof of the long-term advantages of mesh augmentation in risk groups.

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Cited by 10 publications
(7 citation statements)
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“…The findings of this study are consistent with similar works 16,[18][19][20][23][24][25] on the use of fibrin glue as the method of fixation of surgical meshes. The fixing of PP meshes with glue formed fewer adhesions when compared to suture fixation, with significance level of 0.01.…”
Section: Discussion Discussion Discussion Discussionsupporting
confidence: 93%
“…The findings of this study are consistent with similar works 16,[18][19][20][23][24][25] on the use of fibrin glue as the method of fixation of surgical meshes. The fixing of PP meshes with glue formed fewer adhesions when compared to suture fixation, with significance level of 0.01.…”
Section: Discussion Discussion Discussion Discussionsupporting
confidence: 93%
“…18 PMA relative to PSC, even when affixed with fibrin glue alone, has been demonstrated to significantly increase the tensile strength of repair in animal models. 43 PMA most likely creates a loadsharing interface with mesh to minimize hernia formation. One potential concern related to utilization of PMA may be that the use of mesh, particularly a synthetic mesh, in higher risk patients at risk for infection or wound complications; however, some encouraging data are being published that demonstrate relatively favorable outcomes with mesh in contaminated hernia repairs.…”
Section: Discussionmentioning
confidence: 99%
“…In the experimental study conducted by Schug-Pass et al [8] with the biomechanical model of the stamp penetration test, for a standardized incision in muscle tissue the following closure techniques were compared with each other: simple closure with single-button sutures, additional fixation with fibrin glue and augmentation of the suture with 2 cm overlapping TiMesh strips secured with fibrin glue.…”
Section: Methodsmentioning
confidence: 99%