Primary mucinous carcinoma of eyelid: A rare clinical entity

Abstract

Primary cutaneous mucinous carcinoma of the eyelid, a rare pathologic entity, is an adenocarcinoma of the eccrine glands. Though it has low metastatic potential, it does have a significant recurrence rate. We present the occurrence, clinical and histological features, and management of this tumor in a 62-year-old male who presented with a recurrent, firm, nodular left lower lid lesion. He underwent excision with a 5 mm margin and the defect was repaired with a Mustarde's cheek rotation flap. A full oncological screening, including whole-body Positron Emission Tomography scan, excluded the presence of primary mucinous carcinoma elsewhere and any metastatic spread. This case underscores the importance of considering this tumor in recalcitrant eyelid lesions and highlights the pathology of this tumor.

Primary mucinous adenocarcinoma of the scalp: A case report and literature review

“…These tumours are considered low-grade malignant neoplasms with an indolent course, having a tendency for local recurrence (19.6%) and metastasis (6.1%) after surgical treatment over a mean follow-up period of 37.4 months [21] , with most metastases being to the regional lymph nodes [9,10] . Distant metastases have been reported in 2–7 percent of affected patients [6] .…”

Mucinous Eccrine Carcinoma

“…MEC tumors are typically avascular, which may explain the low rate of metastasis. 18 The authors speculate that the involvement of the lacrimal gland in the present case was a result of direct extension (Fig. 2) Clinically, tumors that demonstrate ulceration, tenderness, and erythema are at higher risk for metastasis.…”

Primary Mucinous Eccrine Adenocarcinoma – A Rare Malignant Cutaneous Adnexal Neoplasm at an Unconventional Site

“…Men are more affected than women in a 2:1 ratio. They tend to occur more frequently in elderly individuals (average age 62y, range 34-84 y) [3]. Cutaneous mucinous carcinomas may present with a variety of clinical presentations.…”