Primary necrotizing fasciitis of the breast in a young patient, a case report

Molla, Yohannis Derbew; Kassa, Samrawit Andargie

doi:10.1016/j.ijscr.2022.107844

Cited by 3 publications

(5 citation statements)

References 16 publications

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“…NF initially defined by Wilson in 1952, is a rapidly progressive, life-threatening bacterial infection causing tissue necrosis along fascial planes [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…Factors predisposing to NF include advanced age, alcoholism, obesity, chronic renal failure, cirrhosis, HIV, diabetes, hypertension, use of non-steroidal anti-inflammatory drugs, and immunosuppression (corticoids, chemotherapy, immunosuppressants). The post-partum period and breastfeeding are also risk factors due to weakened immunity [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…Initial empiric broad-spectrum antibacterial therapy is recommended, covering Gram-positive, Gram-negative, and anaerobic organisms [ 4 ]. Antibiothrrapy should be adjusted according to the results of wound or blood cultures.…”

Section: Discussionmentioning

confidence: 99%

“…Smoking Right >3 1 Staphylococcus aureus , Klebsiella pneumoniae , and Acinetobacter baumanii . Staphylococcus epidermidis cefazolin gentamy- cin Yes Debridement Partial mastectomy VAC recovered RJ Klapper et al [ 25 ] 2022 68 Primary hypertension, hyperlipidemia, DM Right 5 1 Proteus species with gram stain positive for Gram-positive cocci vancomyci piperacillin-tazobactam NO Repeated debridement recovered YD Molla et al [ 4 ] 2023 28 Primary Breast feeding Right >2 NA None Ceftriaxone Metronidazol penicillin Yes Repeated debridement partial mastectomy recovered Our case 2023 26 Primary Breast feeding Right 9 1 Staphylococcus aureus , Klebsiella pneumoniae , and Acinetobacter baumanii . Ceftriaxone Metronidazole Gentamicin Yes debridement partial mastectomy Died of severe sepsis …”

Section: Discussionmentioning

confidence: 99%

“…In advanced cases of breast NF, total mastectomy is often performed to control the infection source. Various reconstruction options are available, including skin grafts, delayed closure, local tissue rearrangement, and flap reconstruction [ 4 ]. According to the study by Yuchen Cai, the mortality rate was 12.5 %( n = 40) [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Uncommon presentation of necrotizing fasciitis affecting the breast in a young breastfeeding patient: Case report

Benlghazi,

Benali,

Belouad

et al. 2024

International Journal of Surgery Case Reports

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“…NF initially defined by Wilson in 1952, is a rapidly progressive, life-threatening bacterial infection causing tissue necrosis along fascial planes [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Uncommon presentation of necrotizing fasciitis affecting the breast in a young breastfeeding patient: Case report

Benlghazi,

Benali,

Belouad

et al. 2024

International Journal of Surgery Case Reports

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Fasciite nécrosante postmastectomie et reconstruction mammaire immédiate par prothèse : premier cas rapporté

Piette,

Ungerer,

Roulot

et al. 2024

Annales de Chirurgie Plastique Esthétique

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Necrotizing Fasciitis in a Lactating Breast: A Case Report and Literature Review

Janjua,

Mohammedelfateh,

Vanapalli

et al. 2023

Breast Glob J

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Introduction: Necrotizing fasciitis (NF) is a serious, rapidly progressive disease with significant maternal morbidity and mortality. This case report highlights the rare occurrence of NF in a lactating breast. Patient concerns: A 3-week postnatal young patient exclusively breastfeeding developed left breast engorgement and pain and received two courses of antibiotics for left mastitis. At 6 weeks postnatal, she presented to the hospital with a left breast abscess and fever. Diagnosis: Inflammatory markers were raised. Ultrasound confirmed the presence of a breast abscess. Intervention: The patient was started on antibiotics, and ultrasound-guided aspiration was performed. However, the skin turned black with a rapidly spreading infection; subsequently, she had a debridement of necrotic breast tissue and a biopsy in the theater. Histology confirmed a diagnosis of NF. Outcome: A wound dressing with negative pressure wound therapy was applied. The patient was prescribed Cabergoline 0.25 mg every 12 hours for 2 days to stop milk production. She responded well to an autologous skin graft by the breast team and was discharged. Conclusion: The report emphasizes the importance of considering NF as a potential diagnosis in cases of infection in a lactating breast unresponsive to conventional treatment. Early diagnosis and prompt treatment with antibiotics, surgical debridement, and multidisciplinary care are prudent to prevent adverse sequelae, such as sepsis, partial/total mastectomy, and psychological distress. A biopsy is mandatory to exclude coexistent malignancy.

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Primary necrotizing fasciitis of the breast in a young patient, a case report

Cited by 3 publications

References 16 publications

Uncommon presentation of necrotizing fasciitis affecting the breast in a young breastfeeding patient: Case report

Uncommon presentation of necrotizing fasciitis affecting the breast in a young breastfeeding patient: Case report

Fasciite nécrosante postmastectomie et reconstruction mammaire immédiate par prothèse : premier cas rapporté

Necrotizing Fasciitis in a Lactating Breast: A Case Report and Literature Review

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