Primary non-functional pancreatic paraganglioma: A case report and review of the literature

Abstract

Primary pancreatic paragangliomas are rare. They are mainly non-functional tumours that lack typical clinical manifestations. Definite diagnosis relies on histopathology and immunohistochemistry, and the main treatment is surgery. We report here a case of primary, non-functional, pancreatic paraganglioma in a 49-year-old woman. The tumour was approximately 5.0 × 3.2 ×4.7 cm in size and located in the pancreatic neck and body. We undertook 3D laparoscopic complete resection of the tumour. The patient developed a pancreatic fistula (biochemical leak) post-surgery, but she recovered and was discharged from hospital 11 days after surgery. We describe this case study and briefly summarize previous related reports.

Visual analytics identifies key miRNAs for differentiating peripancreatic paraganglioma and pancreatic neuroendocrine tumors

“…Retroperitoneal PGLs, although rare, can occur in the vicinity of or within the pancreas, resembling primary pancreatic lesions. To date, literature records have documented approximately 56 peripancreatic PGLs (2,6,(40)(41)(42)(43)(44)(45)(46). Distinguishing between PANNETs and PGLs is crucial for appropriate patient management, both preoperatively and postoperatively.…”