Primary Non-Hodgkin's Lymphoma of the Stomach: Endoscopic Diagnosis and the Role of Surgery

Taal, B.G.; Burgers, J. M. V.

doi:10.3109/00365529109111227

Cited by 39 publications

(21 citation statements)

References 15 publications

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“…13,14 Especially in stages I and II, it has been reported that excellent local tumor control can be achieved without resection, with a fair prognosis. 15,16 Unlike gastric NHL, there has not been any definite evidence as to the success of conservative therapy for duodenal NHL. Therefore our patient was operated, and the duodenal lesion proved histologically to be MALToma localized to the bulb (Fig.…”

Section: Discussionmentioning

confidence: 99%

Lymphoma arising in mucosa-associated lymphoid tissue of the duodenal bulb

Kawai¹,

Tada

Yokoyama

et al. 1998

Journal of Gastroenterology

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We report a case of low-grade B-cell lymphoma of the duodenal bulb arising from mucosa-associated lymphoid tissue. A barium swallow and an endoscopic examination showed multiple elevated, irregularly contoured lesions limited to the duodenal bulb. Endoscopic biopsy specimens were highly suggestive of non-Hodgkin's lymphoma. The resected specimen showed a gyriform mucosal elevation measuring 3 x 2cm in extent, with multiple small polypoid elevations scattered around it. Histologically, the small lymphocytes constituting the tumor infiltrated the duodenal mucosa and submucosa. The neoplastic centrocyte-like cells tended to grow around reactive lymphoid follicles and to invade epithelial structures, forming characteristic lymphoepithelial lesions. Monoclonal proliferation of the lymphoid tissue was demonstrated by the polymerase chain reaction method. The histologic appearance and the demonstration of monoclonality fulfilled the criteria for malignant lymphoma arising from mucosa-associated lymphoid tissue, which is extremely rare in the duodenum.

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Section: Discussionmentioning

confidence: 99%

Lymphoma arising in mucosa-associated lymphoid tissue of the duodenal bulb

Kawai¹,

Tada

Yokoyama

et al. 1998

Journal of Gastroenterology

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“…Aufgrund der derzeitigen Literaturdaten ist die operative Tumorresektion jedoch lediglich als eine von mehreren therapeutischen Optionen zu betrachten. So waren die Langzeitüberlebensra-ten einer alleinigen Strahlentherapie mit denen eines operativen Vorgehens vergleichbar (35). Zumeist wird jedoch ein multimodales Vorgehen praktiziert.…”

Section: Diskussionunclassified

Dünndarmileus bei intestinalem Marginalzonen-B-Zell-Lymphom des MALT

Brueck¹,

Barton²,

Rauber³

et al. 2001

Dtsch med Wochenschr

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“…Lesions are usually hypoechoic although few hyperechoic cases have been reported. 12 Infiltrative carcinoma tends to have a vertical growth in gastric wall, while lymphoma tends to show mainly a horizontal extension and more involvement of perigastric lymph nodes. 13 EUS is highly accurate in detecting the depth of lymphomatous infiltration and the presence of perigastric lymph nodes, thus providing additional information for treatment planning, and can differentiate lymphoma from carcinoma both in early stage and in advanced stage.…”

Section: Diagnosis Endoscopymentioning

confidence: 99%

“…The three main patterns that can be recognized at endoscopy include ulceration, diffuse infiltration, and polypoid mass, which are, however, not specific. 12 Endoscopy, however, is an indispensable tool for the initial diagnosis and follow-up of cases as well as for obtaining biopsy specimens. EUS can assess the extent of lesion and its invasion.…”

Section: Diagnosis Endoscopymentioning

confidence: 99%