Primary orbital liposarcoma: A case report

Chebbi, A.; Hachicha, F; Hssine, L Ben; Feki, O.; Bouayed, E.; Malek, Ines; Zeghal, I; Bellagha, I.; Bouguila, H.; Nacef, L.

doi:10.1016/j.jfo.2014.07.018

Cited by 2 publications

(4 citation statements)

References 15 publications

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“…This neoplasm affects men slightly more often than women, and the average patient age is 53 years. [12]…”

Section: Discussionmentioning

confidence: 99%

“…Due to compression of the orbital structures, manifest signs and symptoms generally consist of painless palpebral fullness, proptosis, reduced visual acuity and occasionally, ptosis. [12345] Because of the infrequency of primary orbital liposarcoma and lack of data, it is difficult to study the behavior and prognostic factors for this kind of tumor. CT scans usually demonstrate a well-defined heterogeneous orbital mass, negative attenuation compatible with fat, and both intra- or extra-conal density.…”

Section: Discussionmentioning

confidence: 99%

“…To date, fewer than 50 cases of primary orbital liposarcoma have been reported. [12] We report a new case of primary orbital liposarcoma.…”

Section: Introductionmentioning

confidence: 99%

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Carunclar mass as the presenting sign of primary orbital liposarcoma

Nabie¹,

Halimi

Bahramani³

et al. 2019

Middle East Afr J Ophthalmol

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This study aims to report a case of primary orbital liposarcoma which presented as caruncle mass. A 45-year-old woman presented to our hospital to evaluate the bumpiness of the caruncle in her left eye. A yellowish nodule , which was firmly attached to the sclera , was seen in the caruncle area and seemed to extend into the orbit. Incisional biopsy revealed myxoid liposarcoma She denied further evaluation and came back with enlarged mass after one year. She underwent lid-sparing exentration and was free of recurrence for 5 years.

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“…This neoplasm affects men slightly more often than women, and the average patient age is 53 years. [12]…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Carunclar mass as the presenting sign of primary orbital liposarcoma

Nabie¹,

Halimi

Bahramani³

et al. 2019

Middle East Afr J Ophthalmol

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“…While liposarcoma is the most common soft-tissue sarcoma in adulthood, in the orbit, this tumor is exceedingly rare, with only 70 reported cases to date. 1–27 In part due to its rarity, orbital liposarcoma remains a challenge to treat. Surgery is the mainstay of management; however, local recurrence is common and most patients eventually require exenteration.…”

mentioning

confidence: 99%

Orbital Liposarcoma: A Surveillance, Epidemiology and End Results Database Study

Chen,

Roelofs,

Baugh

et al. 2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Purpose: Orbital liposarcoma is a challenging tumor to treat due to its rarity and high rate of local recurrence, and the role of radiotherapy and chemotherapy remain unclear. Analysis of big data may improve our overall understanding of orbital disease and role of adjuvant therapies. Methods: Data were extracted from the Surveillance, Epidemiology and End Results (SEER) Research Plus database from 1975 to 2017. All patients with a diagnosis of liposarcoma (ICD-O3 codes 8850-8858, 8869-8862, 8870, 8880, 8881) were included. Cases were divided into 4 groups by primary site: orbit, retroperitoneum, soft tissue, and other. Results: A total of 16,958 patients were included. Patients with orbital involvement were younger and more likely to be female (p < 0.05). Among orbital lesions, myxoid liposarcoma was the most common histologic subtype (6/19; 31.6%) followed by well differentiated (5/19; 26.3%). This differed from the distribution of histologic subtypes encountered elsewhere, for which well-differentiated liposarcoma was the most common (retroperitoneum 979/3,136; 31%, soft tissue 3,493/11,671; 30%, and other sites 497/2,132; 23%, p < 0.05). Dedifferentiated histologic subtype was the second most common subtype found in the retroperitoneum (946/3,136; 30%), whereas it was less common in the orbit (2/19; 11%) and soft tissue (1,396/11,671; 12%) (p < 0.001). Patients with orbital liposarcoma had similar disease-specific mortality compared with soft-tissue location (p = 0.825) and lower disease-specific mortality compared with retroperitoneal location (p < 0.001). When all locations were combined, patients with well-differentiated liposarcoma had the lowest disease-specific mortality. Conclusions: Patients with orbital liposarcoma tend to be younger, female, and have a better prognosis than those with retroperitoneal disease, likely due to the lower incidence of dedifferentiated histologic subtype.

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Primary orbital liposarcoma: A case report

Cited by 2 publications

References 15 publications

Carunclar mass as the presenting sign of primary orbital liposarcoma

Carunclar mass as the presenting sign of primary orbital liposarcoma

Orbital Liposarcoma: A Surveillance, Epidemiology and End Results Database Study

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