Primary orofacial granulomatous involvement of lip and gingiva only: A diagnostic challenge

Bansal, Shweta; Garg, Arun; Khurana, Richa; Bansal, Archisha

doi:10.4103/jisp.jisp_18_20

Cited by 3 publications

(4 citation statements)

References 8 publications

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“…The term oro-facial granulomatosis encompasses several conditions exhibiting similar clinical (mostly persistent enlargement of the soft tissues of the oral and maxillofacial region) and microscopic features (presence of non-caseating granulomas on histological examination), often associated with systemic conditions such as sarcoidosis and Crohn’s disease [ 101 , 102 , 103 , 104 , 105 , 106 ].…”

Section: Granulomatous Diseasementioning

confidence: 99%

“…Melkersson-Rosenthal syndrome is an oro-facial granulomatous disease classically characterized by a triad of symptoms such as oro-facial swelling (mostly of the lip, Figure 12 a) recurrent peripheral facial nerve palsy and fissured tongue. Such clinical signs may occur synchronously or metachronously also after many years [ 103 , 110 , 111 ]. When just the swelling of the inferior lip is detectable, the disease is known as granulomatous cheilitis or Miescher’s disease.…”

Section: Granulomatous Diseasementioning

confidence: 99%

See 1 more Smart Citation

Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

2021

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Many systemic (infective, genetic, autoimmune, neoplastic) diseases may involve the oral cavity and, more generally, the soft and hard tissues of the head and neck as primary or secondary localization. Primary onset in the oral cavity of both pediatric and adult diseases usually represents a true challenge for clinicians; their precocious detection is often difficult and requires a wide knowledge but surely results in the early diagnosis and therapy onset with an overall better prognosis and clinical outcomes. In the current paper, as for the topic of the current Special Issue, the authors present an overview on the most frequent clinical manifestations at the oral and maxillo-facial district of systemic disease.

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Section: Granulomatous Diseasementioning

confidence: 99%

Section: Granulomatous Diseasementioning

confidence: 99%

Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

2021

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“…Orofacial granulomatosis (OFG) is an uncommon, noninfectious, and non-necrotizing disease, first described by Wiesenfeld in 1985. 1 OFG presents with painless swelling of the lips or face and can involve ulceration, fissuring, or cobblestoning of the lips, tongue, or buccal mucosa. 1,2 The condition is called granulomatous cheilitis (GC), or cheilitis granulomatosa of Miescher, when involvement is limited to the upper or lower lip.…”

Section: Introductionmentioning

confidence: 99%

“…1 OFG presents with painless swelling of the lips or face and can involve ulceration, fissuring, or cobblestoning of the lips, tongue, or buccal mucosa. 1,2 The condition is called granulomatous cheilitis (GC), or cheilitis granulomatosa of Miescher, when involvement is limited to the upper or lower lip. 3 However, the nomenclature used to describe OFG versus GC varies in the literature.…”

Section: Introductionmentioning

confidence: 99%

Granulomatous Cheilitis Preceding Gastrointestinal Manifestations of Crohn's Disease

Eubanks

Seykora

Bandino

2023

The American Journal of Dermatopathology

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We describe a 20-year-old male with no significant medical history who presented with a 1-month history of painless upper and lower lip edema initially treated with antibiotics for suspected cellulitis before arriving to the clinic. After a failed response to that treatment, a lip biopsy was eventually performed and consistent with a diagnosis of granulomatous cheilitis. In addition to oral and topical corticosteroids and tacrolimus, the patient adopted the cinnamon-and benzoate-free diet with some improvement of his lip swelling. Persistent mild tachycardia led to a cardiology referral for further evaluation and sarcoidosis workup. A gastroenterology consult was placed to correlate his presentation with Crohn's disease. The cardiology workup was noncontributory, and the patient was ultimately diagnosed with Crohn's disease after evaluation with laboratory studies and colonoscopy. This case highlights the need to evaluate for Crohn's disease in patients who present with granulomatous cheilitis, even in the absence of gastrointestinal symptoms, and the potential benefit of incorporating a cinnamon-and benzoate-free diet in treatment.

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Orofacial Granulomatosis

Laskaris

2023

Periodontal Manifestations of Local and Systemic Diseases

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Primary orofacial granulomatous involvement of lip and gingiva only: A diagnostic challenge

Cited by 3 publications

References 8 publications

Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview

Granulomatous Cheilitis Preceding Gastrointestinal Manifestations of Crohn's Disease

Orofacial Granulomatosis

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