Primary ovarian carcinoid: A report of two cases and a decade registry

Metwally, Islam H.; Elalfy, Amr F.; Awny, Shadi; Elzahaby, Islam A.; Abdelghani, Reham M

doi:10.1016/j.jnci.2016.06.003

Cited by 26 publications

(27 citation statements)

References 52 publications

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“…Primary carcinoid tumor of the ovary represents less than 1% of all carcinoid tumors and less than 0.1% of all ovarian neoplasms [4].…”

Section: Discussionmentioning

confidence: 99%

Ovarian carcinoid tumor: Comparing two cases with different histological patterns

Chun-hung¹,

Shui-ying²

2021

J Case Rep Images Obstet Gynecol

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Introduction: Ovarian carcinoid is a well differentiated neuroendocrine tumor, which has similar features as those counterparts in gastrointestinal tract.Case Series: We present here two cases of carcinoid tumor arising at ovary, which presented as ovarian mass. Histopathology examination and immunohistochemical studies revealed neuroendocrine tumor. This article illustrates two cases of ovarian carcinoid which show different histological pattern and clinical presentation. Conclusion:The clinician needs to be aware of the clinical symptoms of carcinoid syndrome. Coupled with blood test of 5-HIAA, surgical resection is beneficial for patients. The clinical presentation correlates well with the histological subtypes.

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“…Primary carcinoid tumor of the ovary represents less than 1% of all carcinoid tumors and less than 0.1% of all ovarian neoplasms [4].…”

Section: Discussionmentioning

confidence: 99%

Ovarian carcinoid tumor: Comparing two cases with different histological patterns

Chun-hung¹,

Shui-ying²

2021

J Case Rep Images Obstet Gynecol

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“…Premenopausal women may be approached with a fertility-sparing surgery but with careful staging to exclude occult metastases. 12,13 The role of systemic chemotherapy in patients with metastatic carcinoid is unclear and is not recommended 14 as no chemotherapy regimen has demonstrated a survival benefit or progressionfree survival.…”

Section: Discussionmentioning

confidence: 99%

Ovarian Carcinoid: a Rare Experience

et al. 2019

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Carcinoid tumors are neuroendocrine tumors. They occasionally secrete serotonin and associated factors that result in a unique constellation of features termed carcinoid syndrome. We report a case of primary ovarian carcinoid, which is a rare condition. A 54 year old lady presented at Obstetric Gynecology Depatment of NMCTH with history of gradually increasing mass in lower abdomen for 3 years. She also had intermittent flushing of face, sweating, shortness of breath, and multiple episodes of loose stools. Examination revealed a mobile mass felt separate from the uterus. Ultrasound, tumor markers and CT scan abdomen were performed. She then underwent staging laparotomy. Histopathology and immunohistochemistry were suggestive of neuroendocrine tumor. HAfter surgery her symptoms disappeared and she was discharged on the 4th postoperative day.

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“…Surgery is the best treatment for carcinoid tumors in general, and in simulation with bronchial carcinoids, we may argue in favor of conservative resection which may be repeated (Caplin et al 2015). This local resection may be very aggressive and may include operations like segmental colon resection, hemicolectomy, low anterior or abdominoperineal resections of the rectum, or even liver resection and tubo-ovariectomy (Metwally et al 2016). In such situations, open surgery is preferred to laparoscopic one as it gives better exploration and easier handling.…”

Section: Discussionmentioning

confidence: 99%

Primary carcinoid tumors at atypical sites: surgery is mandatory and size determines survival—an Egyptian study

Moustafa

Saied

2019

Bull Natl Res Cent

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Background: Carcinoids at atypical sites are rare and mostly asymptomatic. In the majority, they show normal levels of serotonin and its metabolites in plasma and urine, resulting in a relatively late diagnosis and hence guarded prognosis. The relatively large size and repeated local recurrences are features of carcinoids at atypical locations and may direct the attention to its possible existence. Patients and methods: A report of six cases of carcinoid tumors in the breast, abdominal paravertebral region, duodenum, ovary, and stomach is given. Blood serotonin, plasma, and urine 5-hydroxyindole acetic acid were determined for cases suspected to have carcinoid syndrome. Those presented with a mass were radiologically studied by CT or MRI, and if a biopsy was taken (or the mass removed), keratin, CEA, and chromogranin for argentaffin reaction were studied. Follow-up was for 15 months, and a second surgery was done for the two cases (1 and 5). Results: Except for case 4, all patients were females. The symptoms and clinical findings in the six cases were vague and did not raise the possibility of a carcinoid. Repeated local recurrence was the clue for the diagnosis. The enrolled six cases had no common features that may point or suggest the presence of neither carcinoid tumor nor syndrome. Also, there was no relation between the site and size of the tumor and the detection of the manifestations of carcinoid syndrome. Additionally, in one case (case 1), the originally non-functioning lesion turned active when recurrence happened. Conclusion: Carcinoid tumors at atypical sites are low-grade malignant neoplasms with a good long-term prognosis if correctly managed. Routine aggressive resection or even debulking is the treatment of choice whenever possible, even in recurrent cases. The survival of patients depends basically on the tumor size and/or the presence of distant metastases. Treatment by somatostatin analogy is usually mandatory if carcinoid syndrome is present.

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Primary ovarian carcinoid: A report of two cases and a decade registry

Cited by 26 publications

References 52 publications

Ovarian carcinoid tumor: Comparing two cases with different histological patterns

Ovarian carcinoid tumor: Comparing two cases with different histological patterns

Ovarian Carcinoid: a Rare Experience

Primary carcinoid tumors at atypical sites: surgery is mandatory and size determines survival—an Egyptian study

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