Primary ovarian lymphoma

Lim, Yu Hui; Tay, Adriel You Wei; Chew, Sung Hock; Aggarwal, Ieera Madan

doi:10.1136/ijgc-2021-003022

Cited by 3 publications

(3 citation statements)

References 4 publications

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“…Until the lack of lymphoid tissue in normal ovaries has contributed to a lack of consensus regarding the tissue origin and pathogenesis of POL [10] . Some researchers hypothesize that chronic in ammatory stimulation of the ovary may play a role in the development of POLs, while others speculate that the lesions may arise from the lymphoid component of teratomas or malignant transformation of primitive reticular cells in the ovarian stroma [6,13] . In their investigation of 37 oophorectomy specimens, Skodras et al con rmed the presence of scattered lymphocytes and small lymphoid aggregates through IHC analysis.…”

Section: Discussionmentioning

confidence: 99%

The present state of primary ovarian lymphoma: a case report and twenty years of analysis

Liu,

Xu,

et al. 2024

Preprint

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Objective To analyze the clinical and imaging characteristics of primary ovarian lymphoma (POL) from the perspective of radiologists. Materials and Methods The clinical and imaging data of a 52-year-old patient diagnosed with POL was retrospectively analyzed in this study. A review and summary of similar cases reported in English over the past twenty years, as available in the PubMed database, were also conducted. Results The occurrence of POL is not limited by age but is more commonly observed in the forties years old. Clinical manifestations of POL are often nonspecific, presenting as an abdominal mass, abdominal pain, and ascites. The most prevalent histological subtype of POL is diffuse large B cell lymphoma. Imaging features are helpful for diagnosis, such as “ovarian retention sign”, “large ovaries touching each other”, and “vascular floatation”. Conclusion Imaging plays a crucial role in the diagnosis of POL, with radiologists serving as a pivotal role in furnishing essential diagnostic data to assist clinicians in devising suitable treatment strategies, preventing unnecessary surgical interventions.

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Section: Discussionmentioning

confidence: 99%

The present state of primary ovarian lymphoma: a case report and twenty years of analysis

Liu,

Xu,

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…In this case, CA-125 and LDH elevation, patient age, heterogeneously enhancing pelvic mass on CT, and the finding of malignant neoplasm with small round cells on intraoperative frozen section highly favored the diagnosis of dysgerminoma. Histologically, NHL can resemble dysgerminoma, granulosa cell tumor, small cell neuroendocrine carcinoma, small cell carcinoma of hypercalcemic type, and undifferentiated carcinomas ( Vang et al, 2001 , Lim et al, 2021 ). As such, the diagnosis of ovarian NHL is typically not made until immunohistochemical studies can be performed ( van Dorp et al, 2013 ).…”

Section: Discussionmentioning

confidence: 99%

“…Menstrual recovery and spontaneous pregnancy have been frequently observed in reproductive-aged women receiving chemotherapy for NHL ( Elis et al, 2006 , Gharwan et al, 2016 ). Both ovaries are commonly involved in primary ovarian lymphoma, and premenopausal patients with this presentation may undergo bilateral oophorectomy prior to receiving a final pathologic diagnosis of lymphoma ( Dimopoulos et al, 1997 , Pectasides et al, 2008 , Lim et al, 2021 ). Even when disease is present in both ovaries, fertility-sparing surgical approaches may be feasible if lymphoma is identified on intraoperative frozen section.…”

Section: Discussionmentioning

confidence: 99%