Primary Paraganglioma of the Lung: A Case Report and Literature Review

Jj, Zhang; T, Liu; Peng, Fang

doi:10.1177/147323001204000442

Cited by 17 publications

(12 citation statements)

References 27 publications

(32 reference statements)

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“…Enhanced scan shows significant enhancement. 16 T1W1 of magnetic resonance imaging shows isodensity and low signal. T2W1 shows medium, high, or uneven mixed signal.…”

Section: Discussionmentioning

confidence: 96%

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Primary Pulmonary Paraganglioma

et al. 2015

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Primary pulmonary paraganglioma is a rare disease. We report a case of a 37-year old female patient with space-occupying lesions in the right lower pulmonary lobe during a routine examination without any symptoms. The patient underwent video-assisted thoracoscopic surgery (VATS) resection of the right middle lobe and dissection of hilar and mediastinal lymph nodes under general anesthesia. She recovered without recrudescence. Preoperative diagnosis is difficult. Accurate diagnosis requires pathological examination, and immunohistochemical test is particularly important. Complete resection is the first treatment option for solitary primary pulmonary paraganglioma; however, VATS is a better technique. Given the high local control rates and few complications of radiotherapy, it is considered as a standard treatment.

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“…Enhanced scan shows significant enhancement. 16 T1W1 of magnetic resonance imaging shows isodensity and low signal. T2W1 shows medium, high, or uneven mixed signal.…”

Section: Discussionmentioning

confidence: 96%

“… 3 However, invasive biological behaviors have been reported; these behaviors can cause adjacent lymph node metastasis, 4 such as mediastinal lymph node. 5 In general, most of the primary pulmonary paragangliomas do not show evident clinical symptoms. Few of these symptoms are cough and chest pain.…”

Section: Discussionmentioning

confidence: 99%

Primary Pulmonary Paraganglioma

et al. 2015

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“…Nonfunctional paraganglioma may show moderate enhancement due to the low density of blood vessels inside the tumor. [23] Radiological manifestation of tuberculosis classically involves central necrotic tissue with disseminated foci, fiber proliferation, and calcification around the lesion.…”

Section: Discussionmentioning

confidence: 99%

Clear cell tumor of the lung

Qian

Lu²,

Li³

et al. 2016

Medicine

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Background:Clear cell tumor of the lung (CCTL) is a rare and mostly benign pulmonary tumor arising from perivascular epithelioid cells. We reported 2 cases of CCTL in a 24-year-old man with chest pain and a 59-year-old man with dyspnea.Methods:Their chest CT images revealed a well-defined, homogeneous nodule located in the peripheral region of lung parenchyma. The solid nodule showed intense heterogenous postcontrast enhancement in the arterial phase and a homogenous appearance in the venous phase. The two patients underwent thoracotomy, and pathological examinations, including immunohistochemical studies revealed that both cases were benign clear cell tumors.Results:Due to the fact that only a few cases about CCTL were reported, clinicopathological aspects and radiological characteristics of this type of tumor are not well established.Conclusion:CCTL is a rare and benign primary tumor and majorly occurs in middle-aged and elder people. The finding of a small vessel extending along and partially wrapping up one side of the mass in the CT-enhanced images might be a helpful feature to differentiate CCTL from other lung neoplasms.

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“… 1 Paragangliomas are rare tumors that reportedly occur at a rate of two to eight cases per million people each year. 2 Paragangliomas mainly occur in body parts rich in paraganglia, such as the head, neck, mediastinum, posterior peritoneum, and even thyroid. 3 To the best of our knowledge, fewer than 30 cases of paragangliomas with a pulmonary presentation have been documented, and endobronchial involvement is even more rare.…”

Section: Introductionmentioning

confidence: 99%

Primary endobronchial paraganglioma with lymph node metastasis: a case report

Huang

Wu²,

Chen

2021

J Int Med Res

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A paraganglioma is an extra-adrenal tumor of the paraganglia often found in association with sympathetic and parasympathetic nerves. A primary pulmonary paraganglioma generally presents as multiple small tumors or a solitary mass; however, endobronchial involvement is extremely rare. A 49-year-old man was admitted to our hospital because of a chronic cough, intermittent dyspnea, and chest pain. Chest computed tomography revealed a rounded, high-density lesion in the left lower lung lobe. Fiberoptic bronchoscopy demonstrated an endobronchial mass characterized by smooth, hypervascularized mucosa. Transbronchial biopsy of the mass and immunohistochemistry results suggested a paraganglioma. The patient fully recovered after lobectomy and lymphadenectomy. Pulmonary paragangliomas are rarely reported. Complete surgical resection is considered the treatment of choice for pulmonary paragangliomas, and the long-term prognosis is generally good. However, life-long follow-up is mandatory because of the possibility of recurrence and metastasis. This case report adds valuable knowledge to the literature on pulmonary paragangliomas.

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Primary Paraganglioma of the Lung: A Case Report and Literature Review

Cited by 17 publications

References 27 publications

Primary Pulmonary Paraganglioma

Primary Pulmonary Paraganglioma

Clear cell tumor of the lung

Primary endobronchial paraganglioma with lymph node metastasis: a case report

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