Primary pulmonary Hodgkin's lymphoma and a review of the literature since 2006

Cooksley, Nathania A.J.B.; Judge, Daniel; Brown, James S.

doi:10.1136/bcr-2014-204020

Cited by 27 publications

(32 citation statements)

References 33 publications

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“…The criteria for the diagnosis of PPDLBCL include the following: pathological and immunohistochemical features of DLBCL, a primary lesion restricted to the lung (parenchyma and/or bronchi) with or without minimal hilar lymph node involvement, and clinical, radiological, and pathological exclusion of the disease at distant sites. 4 , 5 Our case meets these criteria.…”

Section: Discussionmentioning

confidence: 52%

Primary Pulmonary Diffuse Large B-Cell Lymphoma on FDG PET/CT-MRI and DWI

Wang

et al. 2015

Medicine

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Primary pulmonary diffuse large B-cell lymphoma (PPDLBCL) directly arising from lung tissue is extremely rare. It may usually be misdiagnosed as inflammation including pulmonary tuberculosis, even lung cancer, because its clinical symptoms and signs are often nonspecific. The final diagnosis usually depends on lung biopsy. Herein, we report a case of PPDLBCL and review of diagnosis of this disease, particularly in radiology.A 44-year-old man presented with cough, sputum, and intermittent chest pain for 4 weeks. Multiple radiological examinations showed an irregular mass in the right upper lobe with ground-glass opacities around it and air-filled bronchi in the consolidation. Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography-magnetic resonance imaging (MRI) detected positive FDG uptake, and diffusion-weighted imaging indicated abnormal hyperintension in the lesion. Inflammation was suspected, but malignance cannot be excluded.Finally, ultrasound-guided fine-needle aspiration cytology was performed for histological examination and definitive diagnosis yielded lymphomatous cells infiltration in the right upper lobe.This report emphasizes the significance of multimodality radiological examinations. Multimodality imaging contributes to proper diagnosis, staging, and management of lymphomas.

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Section: Discussionmentioning

confidence: 52%

Primary Pulmonary Diffuse Large B-Cell Lymphoma on FDG PET/CT-MRI and DWI

Wang

et al. 2015

Medicine

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“…PPHL commonly presents as a lung mass and rarely as an endobronchial lesion 2. Fewer than 100 cases of PPHL have been reported 3.…”

Section: Discussionmentioning

confidence: 99%

“…PPHL occurs predominantly in women with a bimodal age distribution, with the first incidence peak occurring in the third decade, and the second being in the sixth/seventh decade 3. There are three main diagnostic criteria for PPHL: (1) the tumour needs to be confined within the lung tissue with or without involvement of the hilar or mediastinal lymph nodes, (2) pathological results should comply with Hodgkin’s lymphoma and (3) exclusion of other pathological conditions outside the lungs 2. Our patient had skeletal metastasis at the time of diagnosis; hence, the disease cannot be characterised as PPHL.…”

Section: Discussionmentioning

confidence: 99%

Hodgkin’s Lymphoma presenting as an obstructing endobronchial mass—A rare presentation

Abid¹,

Khan

Lone

2018

BMJ Case Reports

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We report a case of Hodgkin's lymphoma presenting as an endobronchial mass in a 40-year-old man with history of 8 months of non-specific symptoms like cough, fatigue and weight loss. Initially he was treated with broad-spectrum antibiotics for suspicion of pneumonia without recovery. Radiographic work-up showed cavitary consolidation of the upper lobe of the left lung, followed by bronchoscopy which showed obstructing mass of the upper lobe of the left lung mimicking primary lung carcinoma. Immunohistochemical staining of the specimen was suggestive of Hodgkin's lymphoma. The patient responded well to the chemotherapy regimen.

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“…127 There are very limited data to evaluate survival specific to primary pulmonary lymphoma, and larger series suggest similar outcomes to other types of NHL. 128 Overall survival rates from the ART era in HIV-infected patients with NHL range from 56 to 67%. 124,129…”

Section: Pulmonary Lymphomamentioning

confidence: 99%

Lung Malignancies in HIV Infection

Sigel

Pitts

Crothers

2016

Semin Respir Crit Care Med

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Pulmonary malignancies are a major source of morbidity and mortality in HIV-infected persons. Non-AIDS defining lung cancers (mostly non-small cell lung cancers) are now a leading cause of cancer death. HIV-associated factors appear to affect the risk of lung cancer and may adversely impact cancer treatment and outcomes. HIV infection also may modify the potential harms and benefits of lung cancer screening with computed tomography. AIDS-defining lung malignancies include pulmonary Kaposi sarcoma and pulmonary lymphoma, both of which are less prevalent with widespread adoption of antiretroviral therapy.

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Primary pulmonary Hodgkin's lymphoma and a review of the literature since 2006

Cited by 27 publications

References 33 publications

Primary Pulmonary Diffuse Large B-Cell Lymphoma on FDG PET/CT-MRI and DWI

Primary Pulmonary Diffuse Large B-Cell Lymphoma on FDG PET/CT-MRI and DWI

Hodgkin’s Lymphoma presenting as an obstructing endobronchial mass—A rare presentation

Lung Malignancies in HIV Infection

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