Primary Retropharyngeal Neuroblastoma in an Infant: A Case Report with Literature Review

Lee, Jae Hyung; Kim, Eun Soo; Lee, Yul; Lee, Kwan Seop; Kwon, Mi Jung; Moon, Jai‐Hee; Kim, Hye Jeong; Yoon, Dae Young

doi:10.3348/jksr.2017.77.4.258

J Korean Soc Radiol

2017

DOI: 10.3348/jksr.2017.77.4.258

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Primary Retropharyngeal Neuroblastoma in an Infant: A Case Report with Literature Review

Jae Hyung Lee

Eun Soo Kim

Yul Lee

et al.

Abstract: Neuroblastoma is a malignant tumor usually occurring in children, which most commonly develops in the abdomen. Primary cervical neuroblastoma has rarely been reported. We present a case of primary retropharyngeal neuroblastoma with an ipsilateral lymph node metastasis, manifesting as a growing neck mass in the retropharyngeal space, in an 11-month old infant. Index terms

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2024

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Spontaneously Regressing Retropharyngeal Neuroblastoma – A Rare Cause of Upper Airway Obstruction in a Neonate: A Case Report with Review of Literature

Piridi,

Manugu,

Kamuni

et al. 2024

Indian Pediatrics Case Reports

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Background: Retropharyngeal masses may rarely cause persistent respiratory distress, stridor, and feeding difficulties in a neonate. We report a rare case of a primary cervical neuroblastoma presenting as a retropharyngeal mass, which underwent spontaneous regression. Clinical Description: A 29-day-old male baby was referred for recurrent vomiting since day 10 of life followed by severe difficulty in breathing since day 14 of life. At admission, the baby had stridor, cyanosis with respiratory failure, without any facial dysmorphism or cardiovascular involvement. Management and Outcome: After initial stabilization, investigations showed pneumonia in chest X-ray, with no evidence of sepsis. On intubation, a retropharyngeal bulge was noticed which was later confirmed by direct laryngoscopy. Later, computed tomography delineated the soft-tissue mass extending from C2–C5. Endoscopy with marsupialization of the tumor was done, and on histopathological examination, it was diagnosed as a small round blue cell tumor, suggestive of neuroblastoma, along with positive immunohistochemistry. According to the International Neuroblastoma Staging System, the tumor belonged to Stage I. As the baby had started improving clinically, further management by a multidisciplinary team was collectively decided to continue conservative observation. On follow-up, there was spontaneous regression in size of tumor with no recurrence of symptoms till the last follow-up at 11 months. Conclusion: Neuroblastoma, the most common solid tumor malignancy in children, may rarely have a primary cervical presentation, causing breathing and feeding difficulties. Depending on the course of symptoms, a strategy of observation and close monitoring by a multidisciplinary team can be taken, as such tumors may regress spontaneously.

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Spontaneously Regressing Retropharyngeal Neuroblastoma – A Rare Cause of Upper Airway Obstruction in a Neonate: A Case Report with Review of Literature

Piridi,

Manugu,

Kamuni

et al. 2024

Indian Pediatrics Case Reports

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show abstract

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Primary Retropharyngeal Neuroblastoma in an Infant: A Case Report with Literature Review

Cited by 1 publication

References 8 publications

Spontaneously Regressing Retropharyngeal Neuroblastoma – A Rare Cause of Upper Airway Obstruction in a Neonate: A Case Report with Review of Literature

Spontaneously Regressing Retropharyngeal Neuroblastoma – A Rare Cause of Upper Airway Obstruction in a Neonate: A Case Report with Review of Literature

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