Primary Sjogren Syndrome at a University Hospital: A Retrospective Analyses

Abstract

BACKGROUNDDiagnosis of primary Sjögren's syndrome (pSS) is based on objective dry eye/mouth assessment, presence of antibodies (e.g., anti-SSA/SSB) and minor salivary gland biopsy (MSGB). However, pSS extraglandular manifestations (EGM) have been increasingly recognized. EULAR Sjögren's syndrome disease activity index (ESSDAI) combines EGM useful for diagnosis and follow-up in pSS. This study aims to describe demographic, clinical, serological, MSGB and EGM findings in 57 pSS patients regularly followed-up at a rheumatology outpatient clinic of a university hospital.