Primary small cell carcinoma of the esophagus

McFadden, David W.; Rudnicki, Marek; Talamini, Mark A.

doi:10.1016/0003-4975(89)90404-9

Cited by 56 publications

(34 citation statements)

References 33 publications

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“…So the typical risk factors for a small cell carcinoma of the lung, ergo alcohol and smoking, can be transferred to our case of the esophagus. In contrast to former series described [22], [26], we found a predominance of SCCE in the middle third of the esophagus followed by the localization in the lower third of the esophagus, but the low differences suggest that the tumour can be found in the lower and middle third in the same proportion. In the upper esophagus SCCE is rarely found (<5%).…”

Section: Discussioncontrasting

confidence: 99%

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Primary small cell carcinoma of the esophagus: patient data metaanalysis and review of the literature

Ziske²,

Ig³

2013

GMS German Medical Science; 11:Doc12; ISSN 1612-3174

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Section: Discussioncontrasting

confidence: 99%

“…Here we present an individual patients’ data metaanalysis in respect of the reviewed published literature. The disease has been described in patients ranging in age between 28–88 years, but most commonly it occurs during the sixth to eighth decades of life [26]. This matches to our median age of 60 years.…”

Section: Discussionsupporting

confidence: 79%

Primary small cell carcinoma of the esophagus: patient data metaanalysis and review of the literature

Ziske²,

Ig³

2013

GMS German Medical Science; 11:Doc12; ISSN 1612-3174

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“…Our patient's renal function was slightly impaired after esophagectomy, so we We elected to use radiation therapy for the metastasis to the oropharynx, which achieved a local complete response. McFadden et al reported that radiotherapy should not be used as the sole primary treatment for a patient with advanced-stage disease, and that the mean survival time was 4.1 months in cases using radiotherapy alone [15]. There are, however, some cases, such as this one, in which radiation therapy alone for localized lesions is effective [16].…”

Section: Discussionmentioning

confidence: 93%

Long-surviving case of advanced esophageal small cell carcinoma with a multidisciplinary treatment approach

et al. 2008

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A 64-year-old man presented with dysphagia and heartburn. Upper gastrointestinal endoscopy showed an irregular type 2 tumor of the lower esophagus. Histological examination of the biopsy specimen revealed undifferentiated carcinoma, small cell type. Subtotal esophagectomy was performed. Two months after the initial surgery, an intradural extramedullary metastasis was found, and tumorectomy was performed. Eight months after the initial surgery, lymph node metastases were found, and alternateweek administration of CPT-11 was begun. Thirteen months after the initial surgery, an oropharyngeal metastasis was identifi ed for which he received radiation therapy with a total dose of 45 Gy. One month later, abdominal CT scan showed multiple liver metastases and a left adrenal metastasis. He received CPT-11 for another 12 months, but eventually succumbed to his disease 30 months after the initial diagnosis. Our case suggests that controlling each of the recurrent lesions with various treatment modalities might lead to prolonged survival.

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“…In the limited disease, after surgical resection, short-term results of chemotherapy and radiotherapy are good, although long-term results are still poor. In a series of 29 patients with limited disease treated with only surgery, average survival was 8 months [12]. Also in a series of 20 patients with limited disease patients treated only with radiotherapy, average survival was 5 months [13].…”

Section: Discussionmentioning

confidence: 99%

A Rare Cause of the Cough: Primary Small Cell Carcinoma of Esophagus—Case Report

Yekeler¹,

Koca

Vural

2012

Case Reports in Medicine

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Primary small cell carcinoma of the esophagus is a relatively rare malignancy. It is highly progressive and poorly prognostic in untreated conditions. In the western populations, the rate of primary small cell carcinoma in all esophageal cancer types is between 0.05% and 2.4%, while it is endemically increasing up to 7.6% in the eastern populations. Most of the cases are in extensive stage at the time of diagnosis. Surgery is the treatment of choice in limited stages, but treatment must be multimodal in primary small cell carcinoma of the esophagus. A 47-year-old woman was referred to our clinic with gradually increasing severe dry cough and slight difficulty in swallowing for 20 days. Chest X-ray graphy was normal, and computed tomography of the chest showed multiple mediastinal lymph nodes and hepatic metastases. Her endoscopic examination revealed an endoluminal vegetative mass between 20 cm and 23 cm of her esophagus. The case was reported as small cell carcinoma of the esophagus on histopathological examination. The case was assumed inoperable, and chemotherapy and radiotherapy were planned. We presented a rare cause of the cough and primary esophageal small cell carcinoma in this paper.

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Primary small cell carcinoma of the esophagus

Cited by 56 publications

References 33 publications

Primary small cell carcinoma of the esophagus: patient data metaanalysis and review of the literature

Primary small cell carcinoma of the esophagus: patient data metaanalysis and review of the literature

Long-surviving case of advanced esophageal small cell carcinoma with a multidisciplinary treatment approach

A Rare Cause of the Cough: Primary Small Cell Carcinoma of Esophagus—Case Report

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