The patient was a 72-year-old man. He was referred to our hospital with complaints of obstipation and anemia. Four tumor lesions were detected in his descending colon and sigmoid colon. We performed extended left hemicolectomy with dissection of regional lymph nodes. Pathological examination revealed 1 carcinoma in the sigmoid colon, 5 carcinomas in the descending colon,3 carcinomas in the transverse colon, and lymph node metastasis. All tumors were tubular adenocarcinomas, and 4 carcinomas were adenomas. These findings indicate that this case may be associated with adenoma-carcinoma sequence.