Primary spinal peripheral primitive neuroectodermal tumor with acute presentation: A case report and review of literature

Abstract

Primary spinal primitive neuroectodermal tumors (PNET) is a rare occurrence and carries a poor prognosis. A 13-year old female patient acutely presented with pain in the thoracic region, bilateral lower limb weakness, bladder and bowel dysfunction. Clinically paraplegia with truncal weakness, lower limb deep tendon reflexes of both side were absent and planter reflexes equivocal bilaterally. Preoperative MRI of thoracic spine revealed D4-D6 extradural SOL. A D4-D5 Laminectomy and left Cortico transversectomy done. Pathological findings were consistent with PNET. The clinical, histopathological, and radiological findings of the patient are presented.

Piecing Together a Puzzle of Exceptional Lesions: A Retrospective Study of a Potpourri of 160 Space-Occupying Lesions of the Central Nervous System

“…Primary spinal PNETs are a rare entity with a poor prognosis [ 13 ]. Pathological findings were suggestive of PNET in our patient after correlation of histology and IHC showing CD99, FLi1 to be strongly positive.…”

“…Thoracic spinal psammomatous meningioma is also a rare subtype of meningioma. Psammomatous meningiomas are very rare tumors that complicate the surgical removal in certain cases, yet they are a curable pathology and carry a good prognosis if completely excised (Figure 4 ) [ 13 , 14 ].…”

Primary spinal peripheral primitive neuroectodermal tumour: a report of 3 cases and review of the literature

“…Clinically, pPNET is rarely involved in the spine, and many authors describe spinal pPNET as "extremely rare". The most commonly involved sites are the lumbar spine, followed by the thoracic and cervical vertebrae [2]. Due to its low incidence, most of the related literature consists of case reports [19].…”