Primary Subacute Osteomyelitis of the Axial and Appendicular Skeleton

Ezra, Esther; O, Khermosh; Assia, Ayala; Spirer, Z; Wientroub, Shlomo

doi:10.1097/01202412-199201020-00013

Cited by 20 publications

(23 citation statements)

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“…[5][6][7][8][9][10][11][12][13][14][15][16] Almost one third of our subjects were under 2 years of age, although the median age was similar to those previously reported in all series 5-8,10-16 except one. [5][6][7][8][9][10][11][12][13][14][15][16] Almost one third of our subjects were under 2 years of age, although the median age was similar to those previously reported in all series 5-8,10-16 except one.…”

Section: Discussionsupporting

confidence: 88%

“…reported, [5][6][7][11][12][13][14][15][16] despite the presence of serious predisposing factors in many of our patients. Chronic osteomyelitis in children does not appear to be as recalcitrant a disease as it is in adults, who often present with draining sinuses.…”

Section: Pediatric Chronic Osteomyelitismentioning

confidence: 61%

“…In the previous series where predisposing factors were discussed, none were found. Children in this series were typically treated with intravenous antibiotics for 6 weeks followed by 4 1 ⁄ 2 months of oral antibiotics; this is longer than the courses of antibiotics previously reported [5][6][7][11][12][13][14][15][16] and may reflect the greater number of patients in our series with risk factor(s) and/or the presence of a foreign body at the site of infection. Very few patients seem to have contracted their disease hematogenously, as is usually the case in acute osteomyelitis.…”

Section: Discussionmentioning

confidence: 96%

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Retrospective Assessment of Subacute or Chronic Osteomyelitis in Children and Young Adults

Auh

Binns

Katz

2004

Clin Pediatr (Phila)

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To identify factors associated with and to describe treatment outcomes of pediatric subacute or chronic osteomyelitis (S/CO), we retrospectively identified 52 patients with S/CO from January 1994 to November 1999 seen at a large pediatric hospital infectious disease clinic. S/CO was defined by the following: >10 days of clinical symptoms; radiographic, surgical, or pathologic changes consistent with S/CO; or relapse of prior osteomyelitis. Of these patients 63% were male, median age 9 years. Bones involved included vertebra (19% of subjects), femur (17%), finger (12%), humerus (10%), and tibia (8%). Sixty-five percent had at least 1 risk factor (most commonly hardware, neurologic disease or preceding trauma, sepsis, or surgery). Blood, bone, or wound aspirate cultures were positive in 67%, most commonly for Staphylococcus aureus. Erythrocyte sedimentation rate (ESR) was elevated in 88% of 41 patients at the time of diagnosis. Intravenous antibiotics were given for a median of 6 weeks and oral antibiotics for a median of 4.5 months. One child had a complication. In conclusion, consideration of S/CO should be high when predisposing factors are present. ESR may be useful for determining effectiveness and duration of therapy. With prolonged antibiotic therapy nearly all patients demonstrated resolution of disease.

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Section: Discussionsupporting

confidence: 88%

Section: Pediatric Chronic Osteomyelitismentioning

confidence: 61%

Section: Discussionmentioning

confidence: 96%

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Retrospective Assessment of Subacute or Chronic Osteomyelitis in Children and Young Adults

Auh

Binns

Katz

2004

Clin Pediatr (Phila)

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“…We therefore analysed case series with reported treatment regimes for chronic and sub-acute osteomyelitis in children. We found 14 observational studies, dating back to 1973: four studies were of children with chronic osteomyelitis 17,[20][21][22] eight studies of sub-acute osteomyelitis, 18,[23][24][25][26][27][28][29] and two looked at both chronic and subacute osteomyelitis. 30,31 We found considerable diversity in treatment regimens.…”

Section: Resultsmentioning

confidence: 99%

Systematic review of systemic antibiotic treatment for children with chronic and sub‐acute pyogenic osteomyelitis

Howard‐Jones

Isaacs

2010

J Paediatrics Child Health

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“…In our review of the literature, we failed to come across any reported cases of the acute form in the adult. There have been several reports of talar osteomyelitis in children [1][2][3][4], but these have all been of the subacute form. Indeed, in several extensive reports on osteomyelitis [5][6][7] there are no cases involving the talus.…”

Section: Discussionmentioning

confidence: 99%