Primary syphilis of the anorectal region

Samenius, B

doi:10.1007/bf02616779

Cited by 17 publications

(5 citation statements)

References 8 publications

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“…Most physicians have a tendency to consider rectal ulceration as a neoplasm (7, 8). Similarly in our case symptoms and signs suggested rectal neoplasia and the clinical history did not reveal homosexuality.…”

Section: Discussionmentioning

confidence: 99%

A Case of Primary Syphilis in the Rectum

et al. 2005

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A 30-yr-old man was referred for suspicious rectal cancer because of ulcerated lesions in the rectum and a palpable mass in left inguinal area. Sigmoidoscopy showed two indurated masses and histologic evaluation of biopsy revealed obliterative endarteritis with heavy plasma cell infiltration. Both venereal disease research laboratories (VDRL) and fluorescent treponemal antibody absorption (FTA-ABS) tests were positive. After injection of penicillin G benzathine for 3 weeks, the rectal chancre and the palpable mass disappeared.

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Section: Discussionmentioning

confidence: 99%

A Case of Primary Syphilis in the Rectum

et al. 2005

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“…The yield from conventional hematoxylin and eosin staining is known to be low, and Warthin-Starry staining, which is known to be specific for syphilis, is usually required to identify spirochetes. The initial treatment of patients with rectal syphilis is a single dose of benzathine penicillin G, 2.4 million units in one intramuscular injection as in our case; however, patients with long-standing diseases may require this dose repeated at weekly intervals for three weeks 17,20. Careful serologic and rectal reexaminations at regular intervals are necessary to document eradication of the infection.…”

Section: Discussionmentioning

confidence: 95%

“…The spectrum of endoscopic findings of rectal syphilis appears to be very diverse and includes proctitis, masses, ulcers, and pseudotumors 10,14. The differential diagnosis should include inflammatory bowel disease, proctitis of another etiology, solitary rectal ulcer, chancroid, viral anorectal ulcers (herpes simplex virus and cytomegalovirus), lymphomas, lymphogranuloma venereum, and rectal cancer 14-17. Ulcers of rectal syphilis may be eccentrically located, multiple, or irregular, and two ulcers may be opposite each other in a "kissing" configuration 18.…”

Section: Discussionmentioning

confidence: 99%

Rectal Syphilis Mimicking Rectal Cancer

2010

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Rectal syphilis, known as a great masquerader, can be difficult to diagnose because of its variable symptoms. Gastroenterologists should be aware of the possibility of rectal syphilis when confronted with anorectal ulcers, and should gather a detailed history about sexual preferences and practices, including homosexuality. We report a case of primary rectal syphilis mimicking rectal cancer on radiologic imaging. In this report, we described the clinical, endoscopic, and radiologic features of this rare case.

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“…Sanford and Voelker published the first large series of the disease in 1925, reporting 670 cases of actinomycosis of various anatomical sites. Interestingly they described only 5 cases related to the perianal region [ 21 ]. The infection commonly occurs in the cervicofacial, thoracic, and abdominopelvic regions [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

“…The anorectal form usually begins in an anal crypt where it evolves as a chronic bacterial infection that is characterized by slowly progressing suppurative fibrosing inflammation, development of draining sinus tracts that may discharge characteristic “sulfur granules” and direct dissemination via adjacent tissues [ 21 , 26 ]. The acute phase is rarely recognized due to the insidious onset, and the diagnosis is nearly always late [ 21 ]. It can often be misdiagnosed because it mimics other more common conditions such as malignancy and tuberculosis [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

Perianal Actinomycosis: A Surgeon’s Perspective and Review of Literature

et al. 2021

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Actinomycosis is a serious suppurative, bacterial infection caused by the gram-positive anaerobic Actinomyces species. Primary perianal actinomycosis is rare and challenging for the colorectal surgeon. We aimed to present our experience and compare this with available literature. All patients with isolated Actinomyces on microbiology reports, between January 2013 and February 2021, were identified and reviewed. Data collection was retrospective based on electronic patient records. The site of infection and treatment strategy were examined. Perianal cases were evaluated in depth. All publications available in the literature were interrogated. Fifty-nine cases of positive actinomycosis cultures were reviewed. Six cases of colonization were excluded. Actinomyces turicensis was the most common organism isolated. Five cases of perianal actinomycosis were identified requiring prolonged antibiotic and surgical therapy. Twenty-one studies, most case reports, published since 1951 were also reviewed. Diagnosis of perianal actinomycosis may be challenging but should be suspected particularly in recurrent cases. Prolonged bacterial cultures in anaerobic conditions are necessary to identify the bacterium. An extended course of antibiotic therapy (months) is required for eradication in certain cases.

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Primary syphilis of the anorectal region

Cited by 17 publications

References 8 publications

A Case of Primary Syphilis in the Rectum

A Case of Primary Syphilis in the Rectum

Rectal Syphilis Mimicking Rectal Cancer

Perianal Actinomycosis: A Surgeon’s Perspective and Review of Literature

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