Primary T‐cell Lymphoma of the Uterine Corpus

Shen, Ching‐Ju; Tsai, Eing‐Mei; Tsai, Kun‐Bow; Wu, Ching-Hu; Hsu, Sodio C. N.

doi:10.1016/s1607-551x(09)70388-2

Cited by 8 publications

(14 citation statements)

References 6 publications

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“…In the scarce available literature it is recommended to treat with hysterectomy and bilateral salpingo-oophorectomy, chemotherapy, irradiation or a combination of these [1]. …”

Section: Discussionmentioning

confidence: 99%

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Primary Malignant Lymphoma of the Uterus: A Case Report and Review of the Literature

Samama

Poelgeest

2011

Case Rep Oncol

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Primary malignant lymphomas in the female genital tract are rare. Most cases are non-Hodgkin lymphomas of which diffuse large B-cell lymphomas are most commonly seen. Symptoms are associated with other, more common diseases; therefore, a doctors’ delay can be expected. In this case a woman presented with complaints of urinary obstruction due to a large tumour in the pelvic area. A laparotomy was performed. A very large tumour of the uterus was found with adherence to the pelvic wall and urinary bladder. Diagnostic histological examination showed a diffuse large B-cell lymphoma. Treatment with R-CHOP chemotherapy was started shortly after the operation. The treatment of patients with a primary malignant lymphoma of the uterus should be individualized with the following options: surgery, radiotherapy and/or chemotherapy.

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“…In the scarce available literature it is recommended to treat with hysterectomy and bilateral salpingo-oophorectomy, chemotherapy, irradiation or a combination of these [1]. …”

Section: Discussionmentioning

confidence: 99%

“…The most common diagnosis is diffuse large B-cell lymphoma [1, 2]. Main symptoms are abnormal vaginal blood loss, abdominal pain and/or urinary obstruction.…”

Section: Introductionmentioning

confidence: 99%

Primary Malignant Lymphoma of the Uterus: A Case Report and Review of the Literature

Samama

Poelgeest

2011

Case Rep Oncol

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“…6 Primary extranodal NHL of the female genital tract is a rare condition accounting for around 2% of all extranodal lymphomas. 7 Primary NHL of uterus and cervix is found in around 0.5% where as extranodal NHL involving uterine corpus and bilateral ovaries are extremely rare like this case. 8 Primary uterine lymphoma is defined as disease clinically confined to the uterus at initial time of diagnosis, absence of leukemia and at least several months interval between the appearance of secondary site and the primary site.…”

Section: Discussionmentioning

confidence: 68%

Case of extranodal non-hodgkins lymphoma involving the endometrium and the ovaries: a rare case report

Malempati

Nandan

Babu

2017

Int J Reprod Contracept Obstet Gynecol

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Non-Hodgkin’s lymphoma(NHL) is most commonly encountered during childhood and rarely among the adults. Primary malignant lymphoma in the female genital tract are rare Moreover they present with non-specific symptoms and hence there may be delay in the diagnosis. It is difficult to distinguish this condition from the more common uterine neoplasm such as uterine fibroids or sarcoma. Diffuse large B-cell lymphoma (DLBCL) is most commonly seen among the cases of NHL, contributing to among one third of NHL in the western world. DLBCL is common in elderly population. A 69-year-old postmenopausal woman who came with watery discharge since, 15 days was evaluated clinically and radiologically and was found to have thickened endometrium and enlarged ovaries, for which endometrial biopsy was taken that showed non-secretory endometrium with atrophic changes. Tumor markers found to be normal. TAH+BSO was done and the histopathology showed Non-Hodgkin’s lymphoma, diffuse large B cell type of the endometrium and both ovaries which was confirmed by immune histochemical marker study. PET-CT was done that showed metabolically active para aortic and common iliac lymph nodes thereby she was diagnosed with stage II (Ann Arbor Staging) non-Hodgkin’s lymphoma, hence she received 6 cycles of R-CHOP. As evident in our case, non-Hodgkin’s Lymphoma of the endometrium and the ovaries being an extremely rare condition, high-degree of suspicion is required for its prompt diagnosis and treatment.

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“…In our case masses causing dissapperance of boundary between myometrium and endometrium and showing lobulation was seen and thought as sarcoma radiologically for the initial diagnosis. According to limited literature primary uterine lymphomas could be managed by TAH BSO, chemotherapy, radiation treatment or combination of both (4) . Depending on published litareture, 3 diagnostic criteria are defined for primary uterine lymphomas, 1) tumour is clinically limited to uterus, 2) no atypical cells in periferal vasculature and bone marrow, 3) presence of at least a few months between genital system lymphomas and secondary involvements (16,17) .…”

Section: Discussionmentioning

confidence: 99%

“…Most commonly seen primary genital system lymphoma is diffuse large B cell non-hodgkin lymphoma (NHL) (4,5) .…”

Section: Introductionmentioning

confidence: 99%

The diagnostic challange of an uterine mass: primary uterine lymphoma

Boza¹,

Bostancı²,

Koç³

et al. 2014

J Turk Soc Obstet Gynecol

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Primary T‐cell Lymphoma of the Uterine Corpus

Cited by 8 publications

References 6 publications

Primary Malignant Lymphoma of the Uterus: A Case Report and Review of the Literature

Primary Malignant Lymphoma of the Uterus: A Case Report and Review of the Literature

Case of extranodal non-hodgkins lymphoma involving the endometrium and the ovaries: a rare case report

The diagnostic challange of an uterine mass: primary uterine lymphoma

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