Primary Thrombophilia XIV: Worldwide Identification of Sticky Platelet Syndrome

Vallejo-Villalobos, María Fernanda; Gomez-Cruz, Gisela B.; Cantero-Fortiz, Yahveth; Olivares‐Gazca, Juan Carlos; Olivares-Gazca, Mauricio; Murrieta-Álvarez, Iván; Reyes-Núñez, Virginia; Ruíz‐Argüelles, Guillermo J.

doi:10.1055/s-0039-1688498

“…As a result of our interest in the SPS and with the assistance of various collaborators and of the previously mentioned giant clotters, we have now pieced several features of the SPS which can be summarized as follows [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] :…”

Section: La Troisième…mentioning

confidence: 99%

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2023

Semin Thromb Hemost

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“…As a result of our interest in the SPS and with the assistance of various collaborators and of the previously mentioned giant clotters, we have now pieced several features of the SPS which can be summarized as follows 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 :…”

Section: La Troisième…mentioning

confidence: 99%

Professor Peter Kubisz (1942–2022)—Un hommage à trois étincelles

Ruíz‐Argüelles

¹

2022

Semin Thromb Hemost

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“…51 SPS has been identified and published worldwide: A total of 1783 patients have been published from different parts of the world between 1988 and 2019 and informed that cases have increased in the last 10 years, most of them have been identified in Slovakia, the United States, Mexico, Germany, and Russia. 48…”

Section: Salient Features Of the Sps Phenotypementioning

confidence: 99%

Primary Thrombophilia XVI: A Look at the Genotype of the Sticky Platelet Syndrome Phenotype

García-Villaseñor

¹

,

Bojalil-Álvarez

²

,

Murrieta-Álvarez

³

et al. 2021

Clin Appl Thromb Hemost

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The sticky platelet syndrome (SPS) was described by Mammen in 1983. Since then, scientists in several countries have identified the condition and published cases or series of patients, thus enabling the description of the prevalence of the inherited condition, its salient clinical features, and the treatment of the disease. The diagnosis of the SPS phenotype requires fresh blood samples and special equipment which is not available in all coagulation laboratories. In the era of molecular biology, up to now it has not been possible to define a clear association of the SPS phenotype with a specific molecular marker. Some molecular changes which have been described in platelet proteins in some persons with the phenotype of the SPS are here discussed. Nowadays, the SPS phenotype may be considered as a risk factor for thrombosis and most cases of the SPS developing vaso-occlussive episodes are the result of its coexistence with other thrombosis-prone conditions, some of the inherited and some of them acquired, thus leading to the concept of multifactorial thrombophilia. Ignoring all these evidence-based concepts is inappropriate, same as stating that the SPS is a nonentity simply because not all laboratories are endowed with adequate equipment to support the diagnosis.

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Primary Thrombophilia XIV: Worldwide Identification of Sticky Platelet Syndrome

Cited by 7 publications

References 59 publications

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Professor Peter Kubisz (1942–2022)—Un hommage à trois étincelles

Primary Thrombophilia XVI: A Look at the Genotype of the Sticky Platelet Syndrome Phenotype

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