We introduce the critical Weinstein category -the result of stabilizing the category of Weinstein sectors and inverting subcritical morphisms -and construct localizing 'P-flexibilization' endofunctors indexed by collections P of Lagrangian disks in the stabilization of a point T * D 0 . Like the classical localization of topological spaces studied by Quillen, Sullivan, and others, these functors are homotopy-invariant and localizing on algebraic invariants like the Fukaya category. Furthermore, these functors generalize the 'flexibilization' operation introduced by Cieliebak-Eliashberg and Murphy and the 'homologous recombination' construction of Abouzaid-Seidel. In particular, we give an h-principle-free proof that flexibilization is idempotent and independent of presentation, up to subcriticals and stabilization. In fact, we show that P -flexibilization is a multiplicative localization of the critical Weinstein category, and hence gives rise to a new way of constructing commutative algebra objects from symplectic geometry.