2011
DOI: 10.3171/2010.10.focus10217
|View full text |Cite
|
Sign up to set email alerts
|

Primitive neuroectodermal tumors of the spine: a comprehensive review with illustrative clinical cases

Abstract: Primary spinal primitive neuroectodermal tumors (PNETs) are uncommon malignancies that are increasingly reported in the literature. Spinal PNETs, like their cranial counterparts, are aggressive tumors and patients with these tumors typically have short survival times despite maximal surgery, chemotherapy, and radiation. Because no standard management guidelines exist for treating these tumors, a multitude of therapeutic strategies have been employed with varying success. In this study the authors perfo… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

3
89
1
3

Year Published

2013
2013
2022
2022

Publication Types

Select...
4
3

Relationship

0
7

Authors

Journals

citations
Cited by 51 publications
(96 citation statements)
references
References 85 publications
3
89
1
3
Order By: Relevance
“…The peak age for EWS is 15 to 17 years, being rarer in adults [1,7,8,9]. Primary Ewing's sarcoma of spine has male preponderance with posterior elements of the spine being commonly involved and are mostly extradural-extramedullary.…”
Section: Discussionmentioning
confidence: 99%
See 3 more Smart Citations
“…The peak age for EWS is 15 to 17 years, being rarer in adults [1,7,8,9]. Primary Ewing's sarcoma of spine has male preponderance with posterior elements of the spine being commonly involved and are mostly extradural-extramedullary.…”
Section: Discussionmentioning
confidence: 99%
“…The occurrence in adult age is quite rare [1,7]. The most common primary sites of involvement are the pelvis, femur, tibia, and fibula.…”
Section: Introductionmentioning
confidence: 99%
See 2 more Smart Citations
“…The Ewing's family of tumours comprise of Ewing's sarcoma, extraskeletal Ewing's sarcoma, primitive neuroectodermal tumour (PNET) of bone and soft tissue and chest wall tumour (A skin's tumour).The translocation t (11;22) (q24;q12) is identified in more than 90% of cases of Ewing's sarcoma [5,6]. Spinal involvement most commonly results from metastasis in advanced stages of the disease, while Ewing's sarcoma originating from the spine is rare and extremely rare if the sacrum is excluded [7].…”
Section: Discussionmentioning
confidence: 99%