PRINCESS: Privacy-protecting Rare disease International Network Collaboration via Encryption through Software guard extensionS

Chen, Feng; Wang, Shuang; Jiang, Xiaoqian; Ding, Sijie; Lu, Yao; Kim, Jihoon; Şahinalp, S. Cenk; Shimizu, Chisato; Burns, Jane C.; Wright, Victoria J.; Png, Eileen; Hibberd, Martin L.; Lloyd, David; Yang, Hai; Telenti, Amalio; Bloss, Cinnamon S.; Fox, Dov; Lauter, Kristin; Ohno-Machado, Lucila

doi:10.1093/bioinformatics/btw758

Cited by 90 publications

(67 citation statements)

References 37 publications

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“…Cyber Notary, in this case, described as a traffic safety in electronic transactions over the Internet. It can occur through the form of conventional notary public function, namely authentic automatically or electronically by utilizing the existing public infrastructure and electronic signature [9], To that end, a Notary cyber said should have high qualifications apart from its legal ability as a foundation [8]. The primary function of the cyber notary is doing certification and authentification traffic in electronic transactions.…”

Section: Understanding Cyber Notarymentioning

confidence: 99%

Authority and Power of the Law Relating to Cyber Deed Notary in Indonesia Era Industrial Revolution 4.0

Chamidah¹,

Krustiyati²,

Purwadi³

et al. 2019

IJEAT

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This study aims to determine the authority of the notary in a deed on electronic transactions carried out by the parties domiciled outside the office of a notary and to know the power of a notary deed that created by Cyber Notary in Indonesia. The method used in this research is the approach of legislation (The Statute Approach) and the path of the legal concept analysis (Analytical and Conceptual Approach). The results showed that the authority of the electronic notary deed is not bound by a notary office area so that the legal position same with notary office by deed made by the notary on electronic transactions conducted in the region of the notary office. The strength of the notarial deed made by a cyber notary has not yet ensured legal certainty that the power of a notarial deed made together with the strength of the deed under the hand.

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Section: Understanding Cyber Notarymentioning

confidence: 99%

Authority and Power of the Law Relating to Cyber Deed Notary in Indonesia Era Industrial Revolution 4.0

Chamidah¹,

Krustiyati²,

Purwadi³

et al. 2019

IJEAT

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“…Data encryption implements privacy protection through applying encryption techniques to the raw data, which can still supports certain computations for learning [24][25][26][27][28][29][30]. Although data encryption has a strong capability to protect privacy, it is at the cost of high computation complexity.…”

Section: Related Workmentioning

confidence: 99%

An information-aware visualization for privacy-preserving accelerometer data sharing

Xiao

Zhao

et al. 2018

Hum. Cent. Comput. Inf. Sci.

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In the age of big data, plenty of valuable sensing data have been shared to enhance scientific innovation. However, this may cause unexpected privacy leakage. Although numerous privacy preservation techniques, such as perturbation, encryption, and anonymization, have been proposed to conceal sensitive information, it is usually at the cost of the application utility. Moreover, most of the existing works did not distinguished the underlying factors, such as data features and sampling rate, which contribute differently to utility and privacy information implied in the shared data. To well balance the application utility and privacy leakage for data sharing, we utilize mutual information and visualization techniques to analyze the impact of the underlying factors on utility and privacy, respectively, and design an interactive visualization tool to help users identify the appropriate solution to achieve the objectives of high application utility and low privacy leakage simultaneously. To illustrate the effectiveness of the proposed scheme and tool, accelerometer data collected from mobile devices have been adopted as an illustrative example. Experimental study has shown that feature selection and sampling frequency play dominant roles in reducing privacy leakage with much less reduction on utility, and the proposed visualization tool can effectively recommend the appropriate combination of features and sampling rates that can help users make decision on the trade-off between utility and privacy.

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“…where l Pr[O (1) j ] is the expected number of rows with exactly one write request applied to them, computed as before, and 2l Pr[O (2) j ] is the expected number of rows with exactly two write requests applied to them. Computing Pr[O (2) j ] = m 2 1 l 2 (1 − 1 l ) m−2 , we obtain the value of the expected success rate as:…”

Section: Recovering From Collisionsmentioning

confidence: 99%

“…Their construction is based on a combination of a novel genomic edit distance approximation algorithm and new construction of private set difference size protocols. Also, Chen et al [6] introduce a framework using Intel's Software Guard Extension and hardware for trustworthy computations. This way, secure and distributed computation over encrypted data can be performed, respecting institutional policies and regulations for protected health information.…”

Section: Related Workmentioning

confidence: 99%

AnoniMME: Bringing Anonymity to the Matchmaker Exchange Platform for Rare Disease Gene Discovery

Oprisanu

Cristofaro

2018

Preprint

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Advances in genome sequencing and genomics research are bringing us closer to a new era of personalized medicine, where healthcare can be tailored to the individual's genetic makeup, and to more effective diagnosis and treatment of rare genetic diseases. Much of this progress depends on collaborations and access to genomes, thus, a number of initiatives have been introduced to support seamless data sharing. Among these, the Global Alliance for Genomics and Health runs a popular platform, called Matchmaker Exchange, that allows researchers to perform queries for rare genetic disease discovery over multiple federated databases. Queries include gene variations which are linked to rare diseases, and the ability to find other researchers that have seen or have interest in those variations is extremely valuable. Nonetheless, in some cases, researchers may be reluctant to use the platform since the queries they make (thus, what they are working on) are revealed to other researchers, and this creates concerns with privacy and competitive advantage.In this paper, we present AnoniMME, a novel framework geared to enable anonymous queries within the Matchmaker Exchange platform. We build on Reverse Private Information Retrieval (PIR) to let researchers anonymously query the federated platform, in a multi-server setting, by writing their query, along with a public encryption key, anonymously in a public database. AnoniMME also supports responses, allowing other researchers to respond to queries by providing their encrypted contact details.

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PRINCESS: Privacy-protecting Rare disease International Network Collaboration via Encryption through Software guard extensionS

Abstract: Supplementary data are available at Bioinformatics online.

Cited by 90 publications

References 37 publications

Authority and Power of the Law Relating to Cyber Deed Notary in Indonesia Era Industrial Revolution 4.0

Authority and Power of the Law Relating to Cyber Deed Notary in Indonesia Era Industrial Revolution 4.0

An information-aware visualization for privacy-preserving accelerometer data sharing

AnoniMME: Bringing Anonymity to the Matchmaker Exchange Platform for Rare Disease Gene Discovery

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