“…It is important, in fact, that professionals should be sensitive to the possibility of ISD, because parents, whether or not they recognize ISD, are likely to experience negative side effects. Problems include parental (especially maternal) stress, depression, and marital difficulties, plus daytime sleepiness and irritability in the child and possibly in affected siblings, and restrictions in the frequency and intensity of positive parent-child interaction (Chess & Hassibi, 1986;Durand & Mindell, 1990;Fergusson, 1982;Pritchard & Appleton, 1988;Seymour, 1987). More research is urgently needed into the negative effects of ISD on families and into the generality of any positive effects wrought by effective intervention.…”