2021
DOI: 10.1002/ana.26183
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Prior anticoagulation in patients with ischemic stroke and atrial fibrillation

Abstract: colleagues 1 reported the effect of prior anticoagulation with vitamin K antagonists or direct oral anticoagulants (DOACs) on subsequent stroke severity, utilization of intravenous thrombolysis (IVT), safety of IVT, and 3-month outcomes in patients with ischemic stroke and atrial fibrillation (AF). Prior DOAC therapy was significantly associated with decreased admission stroke severity and a lower rate of IVT. In addition, the adjusted odds ratio (OR; 95% confidence interval [CI]) of DOAC pretreatment for a fa… Show more

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