Chemical management is critical and has an enormous impact on our daily lives. Numerous advancements in chemical production have transformed management facets, most notably vis-à-vis safety, health, and environment. Thus, the scientometric review could depict and analyse publication trends in updating scientific datasets and knowledge in this field. This scientometric review is intended to scrutinise the progress, trends, and updates of publications concerning chemical management in the Scopus and Web of Science databases. The publication patterns and authors’ keywords are among the scientometric parameters examined in this review. The obtained publication lists or metadata in this study were analysed using ScientoPy and VOSviewer software, which displayed the scientometric results graphically. The current study portrayed that the number of publications on chemical management has increased in both databases. The exploratory publications and research areas reveal that efforts to inspect chemical management cover miscellaneous topics and disciplines such as environmental science and ecology, engineering, and agriculture. The most related authors’ keywords concerning chemical management are “Risk management”, “Risk assessment”, and “REACH”. Researchers and practitioners may benefit from this scientometric review since it contains data, concepts, thoughts, and insights that can be employed to bolster their theories and practices in managing chemicals.