Prioritizing contaminants of emerging concern for ecological screening assessments

Molecular and cellular effects of contamination in aquatic ecosystems

“…Molecular and cellular approaches are of value to overcome these limitations as they explore the principal toxicity pathways. Thus, they can alert on specific hazardous potentials of chemicals, and they can assist in grouping chemicals according to their modes of action (Diamond et al 2011;Segner 2011). With the adverse outcome pathway (AOP) concept suggested by Ankley et al (2010)), a framework is available which links data collected from lower levels of biological organization through the use of, e.g.…”

Identifying potential surface water sampling sites for emerging chemical pollutants in Gauteng Province, South Africa

“…Although there is no standardised definition of what exactly an ECP is, Liu et al (2014) defined an ECP as a novel chemical that does not have a regulatory status, but which can potentially be harmful to human health and the environment. However, ECPs have also been defined to include regulated chemicals such as polychlorinated biphenyls (PCBs), as they can cause endocrine disruption (Diamond et al 2011).…”

“…Aquatic ecosystems are a sink for natural and anthropogenic chemicals (Diamond et al 2011). Effective monitoring of the aquatic environment is warranted and ECPs are no exception to this statement.…”

“…Effective monitoring of the aquatic environment is warranted and ECPs are no exception to this statement. However, ECPs are poorly characterised in terms of their presence in water resources and their effects on biota (Diamond et al 2011). Once they enter the ecosystem, ECPs and their degradates can be transported and distributed between major ecological compartments, based on factors such as: how the ECP was originally released into the environment, its degradation rate, its half-life, and partition coefficients (Fent et al 2006).…”

Alterações mitocondriais induzidas por representantes das principais classes de Éteres Difenílicos Polibromados

“…Agências de pesquisas ambientais gastam enormes quantias e esforços para monitorar concentrações de vários compostos orgânicos presentes em águas superficiais, sedimentos, animais aquáticos e ecossistema terrestre (DIAMOND, et al, 2011). Entretanto a carência de dados toxicológicos, principalmente relacionados aos efeitos danosos aos organismos, aos biomarcadores de exposição e potenciais danos ao ambiente, também é uma preocupação relacionada a esses compostos.…”