“…The literature points to clusters of factors affecting decision-making as well as complexity in the decision-making process. Martin et al [64] in a qualitative case study of priority setting (using key document review, interviews, and observations) for new drugs in a hospital formulary in Toronto, Canada, found that formulary decisions are based on a complex cluster of factors including benefit, toxicity, ability of the nurse to administer the drug, and so on. Decision-making seems to be opaque in the sense that the goals of the committees involved in formulary decisions were unclear and the focus on the clinical nature of the drugs did not match the financial factors, which they often needed to consider.…”