Prise en charge des comorbidités cardio-vasculaires chez les jeunes patients souffrant d’une psychose débutante : état des lieux et perspectives thérapeutiques

Frajerman, Ariel; Morin, Vincent; Chaumette, Boris; Kébir, Oussama; Krebs, Marie‐Odile

doi:10.1016/j.encep.2020.03.007

Cited by 4 publications

(2 citation statements)

References 75 publications

(76 reference statements)

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“…Previous studies explained that the etiology of the EBP and DHL is a heterogeneous condition involving biological factors, genetics, depressive episodes, anxiety level, psychosocial aspect, cerebrovascular pathology, disorders of the endocrine system, presence of inflammatory processes, and nutritional status (46,47). Aligned with some previous studies (7,8,23,25,26,39,43,48), it is suggested the existence of a close relationship between hypertension disorders and mental health. The study shows that patients with cerebrovascular disease, especially in the anterior hemisphere, show mood lability.…”

Section: Discussionmentioning

confidence: 78%

“…Thus, the study result shows that the classification of hypertension, especially the elevated blood pressure and hypertension level 1 on their SBP and DPB categories, are correlated to the Quality of Life. A previous study on caretaking depression and mental illnesses in the elderly shows it is more likely to be associated with anxiety (38,39). Hypertension and elevated blood pressure were also associated with anxiety through disruption of the autonomic nervous system, leading to higher variations in blood pressure and cardiovascular events (38,40,41).…”

Section: Discussionmentioning

confidence: 96%

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Male Family Caregivers of Schizophrenic Patients have a Higher Risk of Hypertension and Lower Quality of Life : A Cross-Sectional Study

Prabawati

2023

Gac Méd Caracas

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Background: A limited study has identified the essential information on the physical health of family caregivers with patients with schizophrenia in Indonesia. This study aimed to assess the correlations between blood pressure and quality of life in family caregivers of patients with schizophrenia. Methods: A retrospective and cross-sectional study design used convenience sampling conducted in several mental hospitals in Indonesia. Measurement of a calibrating sphygmomanometer and WHO Quality of Life-BRIEF were used to collect the data from the family caregiver. Participants received questionnaires and signed informed consent.

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Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 96%

Male Family Caregivers of Schizophrenic Patients have a Higher Risk of Hypertension and Lower Quality of Life : A Cross-Sectional Study

Prabawati

2023

Gac Méd Caracas

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Is it possible to stage schizophrenia? A systematic review

et al. 2022

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Introduction A staging model is a clinical tool used to define the development of a disease over time. In schizophrenia, authors have proposed different theoretical staging models of increasing complexity. Therefore, the aims of our study were to provide an updated and critical view of the proposed clinical staging models for schizophrenia and to review the empirical data that support them. Methods Systematic literature review following PRISMA guidelines. From the PubMed database and backward reference search, a total of 141 records were retrieved, but only 20 were selected according to the inclusion criteria: (a) available in English; (b) participants with schizophrenia ≥ 18 years; and (c) theoretical and empirical research studies intended to develop, validate, and/or improve staging models of schizophrenia. Results Different clinical staging models for schizophrenia were identified, information about the proposed stages was tabulated and presented in the Results section (Tables 1, 2). Most of which include neuroimaging, functioning, and psychopathology, but only two models add objective biomarkers and none include patient point of view. However, few models have been psychometrically tested or used small samples and thus have been validated only partially. In addition, five studies proposed therapeutic interventions according to the stage of the disorder from a theoretical point of view. Discussion In conclusion, it is possible to stage schizophrenia, but the models developed have several limitations. Empirical validation and inclusion of more specific biomarkers and measures of other life areas affected by schizophrenia could help in the development of more valid models.

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Risk factors for metabolic syndrome in individuals with recent-onset psychosis at disease onset and after 1-year follow-up

Alonso

Miralles

Algora

et al. 2022

Sci Rep

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Metabolic syndrome (MetS) is a cluster of parameters encompassing the most dangerous heart attack risk factors, associated with increased morbidity and mortality. It is highly prevalent in recent-onset psychosis (ROP) patients. In this pilot study, we evaluated MetS parameters (fasting glucose, high-density lipoprotein (HDL) cholesterol (HDL-c), fasting triglycerides, waist circumference, and systolic and diastolic blood pressure), clinical symptoms, pharmacological treatment, lifestyle, and inflammatory markers in 69 patients with ROP and 61 healthy controls (HCs). At baseline, waist circumference (p = 0.005) and fasting triglycerides (p = 0.007) were higher in patients with ROP than in HCs. At the 1-year follow-up, patients showed clinical improvement, with a reduction in the positive and negative syndrome scale (PANSS) score (p < 0.001), dietary intake (p = 0.001), and antipsychotic medication dose (p < 0.001); however, fasting glucose (p = 0.011), HDL-c (p = 0.013) and waist circumference worsened (p < 0.001). We identified sex, age, BMI, dietary intake, physical activity, daily tobacco use, daily cannabis use, and antipsychotic doses as risk factors contributing to baseline MetS parameters. After 1-year follow-up, those factors plus the PANSS and Calgary Depression Scale for Schizophrenia (CDSS) scores were associated with MetS parameters. Further studies are needed to understand the contributions of the studied risk factors in patients with ROP at onset and during disease progression.

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Prise en charge des comorbidités cardio-vasculaires chez les jeunes patients souffrant d’une psychose débutante : état des lieux et perspectives thérapeutiques

Cited by 4 publications

References 75 publications

Male Family Caregivers of Schizophrenic Patients have a Higher Risk of Hypertension and Lower Quality of Life : A Cross-Sectional Study

Male Family Caregivers of Schizophrenic Patients have a Higher Risk of Hypertension and Lower Quality of Life : A Cross-Sectional Study

Is it possible to stage schizophrenia? A systematic review

Risk factors for metabolic syndrome in individuals with recent-onset psychosis at disease onset and after 1-year follow-up

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