Prise en charge des tumeurs cutanées selon la technique Slow Mohs « en gâteau » : étude rétrospective monocentrique sur 10 ans de 548 patients évaluant l’impact de la diminution des marges

Khaddaj, L.; Martinot-Duquennoy, V.; Guerreschi, P.; Mortier, Laurent; Calibre, C.

doi:10.1016/j.anplas.2021.06.005

Cited by 4 publications

(1 citation statement)

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“…A variant of MMS, named Slow-Mohs, is commonly used. In this MMS variant, tissue samples are not analysed extemporaneously but are fixed and paraffin embedded for a subsequent histological and immunohistochemical evaluation [ 56 , 57 , 58 ]. However, MMS and its variants are a time-consuming technique, and not widely diffused as standard surgery procedure.…”

Section: Discussionmentioning

confidence: 99%

The Role of Postoperative Radiotherapy in the Management of Dermatofibrosarcoma Protuberans: A Multidisciplinary Systematic Review

Fionda,

Loperfido,

Di Stefani

et al. 2024

JCM

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Background: Dermatofibrosarcoma protuberans (DFSP) is a superficial soft tissue sarcoma, and surgical excision is the first-line treatment. The aim of this systematic review is to provide an update about the current indications and clinical results regarding the use of postoperative radiotherapy in DSFP, considering both adjuvant and salvage setting. Methods: We conducted a systematic literature review using the main scientific database, including Cochrane library, Scopus, and PubMed, for any relevant article about the topic, and we considered all available papers without any time restriction. Results: Twenty-two papers, published between 1989 and 2023, were retrieved and considered eligible for inclusion in this review. Regarding the fractionation schedules, most authors reported using standard fractionation (2 Gy/die) with a wide total dose ranging from 50 to 70 Gy. The local control after postoperative radiotherapy was excellent (75–100%), with a median follow-up time of 69 months. Conclusions: After the primary surgical management of DFSP, postoperative radiotherapy may either be considered as adjuvant treatment (presence of risk factors, i.e., close margins, recurrent tumours, aggressive histological subtypes) or as salvage treatment (positive margins) and should be assessed within the frame of multidisciplinary evaluation.

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Section: Discussionmentioning

confidence: 99%