2019
DOI: 10.1002/jac5.1107
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PRN OPINION PAPER: Application of precision medicine across pharmacy specialty areas

Abstract: Clinical pharmacists have been incorporating precision medicine into practice for decades. Drug selection and dosing based on patient‐specific clinical factors such as age, weight, renal function, drug interactions, plasma drug concentrations, and diet are expected as part of routine clinical practice. Newer concepts of precision medicine such as pharmacogenomics have recently been implemented into clinical care, while other concepts such as epigenetics and pharmacomicrobiomics still predominantly exist in the… Show more

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Cited by 12 publications
(12 citation statements)
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“…Precision medicine is already used in many areas of pharmacy practice. 5 Table 1 shows the PGx drug-gene pairs that represent known examples for which clinical pharmacists can optimize therapy.…”
Section: Current Applicationsmentioning
confidence: 99%
See 1 more Smart Citation
“…Precision medicine is already used in many areas of pharmacy practice. 5 Table 1 shows the PGx drug-gene pairs that represent known examples for which clinical pharmacists can optimize therapy.…”
Section: Current Applicationsmentioning
confidence: 99%
“…5 PGxguided medication interventions per 100 patients undergoing PCI could have been made, had multigene PGx results been available at the time of PCI. Further studies are needed to show improved outcomes with multigene PGx testing, given that there are many commonly prescribed medications with actionable PGx recommendations such as proton pump inhibitors, antidepressants, and opioids.…”
mentioning
confidence: 99%
“…The increasing quantity and quality of evidence supporting the use of pharmacogenetics has led to changes in US Food and Drug Administration (FDA) labeling; creation of national and international clinical practice guidelines; an Accreditation Council for Pharmacy Education (ACPE) requirement to include pharmacogenetics in pharmacy school curricula, an American Society of Health-System Pharmacists (ASHP) statement on the pharmacist's role in clinical pharmacogenetics, American College of Clinical Pharmacy (ACCP) commentaries and opinions on the pharmacists applying pharmacogenetics to clinical practice; expanded insurance coverage from Medicare and private payers; and increased clinical implementation within health care institutions. [17][18][19][20][21][22][23][24][25][26] Several of these groups (eg, ACPE, ASHP) state that pharmacists, as the experts in pharmacotherapy, have the responsibility to incorporate pharmacogenetic information into treatment as appropriate.…”
Section: Precision Medicine and The Opioid Epidemicmentioning
confidence: 99%
“…Many of those topics are core elements in the patient care process for pharmacists and are crucial to the education and development of competent pharmacy graduates . Pharmacists must be capable of integrating this knowledge across the spectrum of care, as recently articulated in an ACCP PRN Opinion Paper …”
Section: Focus On Pharmacotherapy Of Conditions and Disease Statesmentioning
confidence: 99%